Evolution of radiotherapeutic techniques

Journal Article · Tue Jan 01 04:00:00 EST 1974 · Gynecol. Oncol., v. 2, no. 3, pp. 314-323

DOI:https://doi.org/10.1016/0090-8258(74)90022-5· OSTI ID:4074994

Brady, L W; Lewis, Jr, G C; Antoniades, J; Prasasvinichai, S; Torpie, R J; Asbell, S O; Glassburn, J R; Schatanoff, D; MacMurray, T

Adenocarcinoma is the most common kind of tumor involving the uterine corpus, occurring in a frequency of 90 percent or better and found predominantly in post-menopausal women. Because of vaginal bleeding, diagnosis is made early and control rates are good. Regional lymph node metastases are found to occur in about 20 percent of all operable patients and more frequently in those with advanced lesions near the cervix. Surgery alone fails not only because of metastases but also because of persistence in the vaginal vault and in the periurethral region. From a theoretical and practical viewpoint, preoperative irradiation is a valuable and important role in the treatment of carcinoma of the endometrium. Treatment calls for a technique that will effectively irradiate the uterine tissue, the vaginal vault, and and the immediate extrauterine tissues in which postsurgical persistence is known to appear. From the standpoint of survival, both preoperative external therapy and preoperative radium therapy are effective with equivalent survival figures. The incidence in our experience of vaginal recurrence in those patients who were irradiated preoperatively with external beam therapy techniques would indicate the need for supplemental radium within the vaginal vault. (auth)

• Research Organization: Hahnemann Medical Coll. and Hospital, Philadelphia
• Sponsoring Organization: USDOE
• NSA Number: NSA-33-015065
• OSTI ID: 4074994
• Journal Information: Gynecol. Oncol., v. 2, no. 3, pp. 314-323, Journal Name: Gynecol. Oncol., v. 2, no. 3, pp. 314-323; ISSN GYNOA
• Country of Publication: United States
• Language: English

Related Subjects

*CARCINOMAS-- RADIOTHERAPY
*UTERUS-- CARCINOMAS
560151* --Biomedical Sciences
Applied Studies--Radiation Effects--Radiation Effects on Animals--Man
EXTERNAL IRRADIATION
INTERNAL IRRADIATION
N48510* --Life Sciences--Radiation Effects on Animals--Man
PATIENTS
RADIATION SOURCE IMPLANTS
RADIUM
SURGERY
SURVIVAL TIME
WOMEN