ON THE EFFECTS OF X-IRRADIATION ON THE CHROMOSOMES OF YOSHIDA SARCOMA CELLS (in Japanese)
Journal Article
·
· Idengaku Zasshi (Japan)
OSTI ID:4071592
The Yoshida sarcoma, a rat ascites tumor, was irradiated with x rays at dosages of 500 r, 1000 r, and 1500 r, and the chromosomes were observed in the tumor cells. It was found that the chromosome-number mode of tumor cells in unirradiated tumor-bearing animals occurred at 40. The chromosomes were morphologically analyzed according to the system of Tjio and Levan (1956), and the number of chromosomes assorted in three morphological groups was 13 for M, 13 for S, and 14 for T. Breaks and translocations of chromosomes were rather common and remarkable in metaphase cells observed in irradiated tumor-animals. It was observed in individual cells that there was no constancy in the number of M, S, and T chromosomes which were unaltered by irradiation. From this result, it seems probable that there is no differential radiosensitivity by chromosomes of different types. Two chromosomes of M type are outstanding as marker elements because of their remarkably large size. In the two marker chromosomes, the frequency distribution of breakage was observed after irradiation, and showed that the breakage was rather frequent on both arms around positions one-fourth distant from centromere. (auth)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-15-022032
- OSTI ID:
- 4071592
- Journal Information:
- Idengaku Zasshi (Japan), Journal Name: Idengaku Zasshi (Japan) Vol. Vol: 35; ISSN IDZAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- Japanese
Similar Records
On the effects of X-irradiation on the chromosomes of Yoshida sarcoma cells. (A preliminary report)
THE EFFECT OF Cr$sup 51$ ON YOSHIDA ASCITES SARCOMA CELLS
ON TRANSPLANTABILITY OF YOSHIDA ASCITES TUMOR CELLS
Journal Article
·
Thu Dec 31 23:00:00 EST 1959
· Idengaku Zasshi
·
OSTI ID:4803518
THE EFFECT OF Cr$sup 51$ ON YOSHIDA ASCITES SARCOMA CELLS
Journal Article
·
Wed Dec 31 23:00:00 EST 1958
· Nichidai Igaku Zasshi (Japan)
·
OSTI ID:4839270
ON TRANSPLANTABILITY OF YOSHIDA ASCITES TUMOR CELLS
Journal Article
·
Mon Dec 31 23:00:00 EST 1962
· Kitakanto Igaku (Kitakanto Medical Journal)
·
OSTI ID:4018453