STUDIES ON RADIOACTIVE CESIUM. II. EFFECTS OF SOME DRUGS ON THE DISTRIBUTION AND EXCRETION OF Cs$sup 137$ IN THE RAT
The effect of deoxycorticosterone acetate (DOCA) and cortisone, as well as CsCl as a carrier, on the deposition rate and urinary and fecal excretion rates of /sup 137/Cs was studied in rnts subcutaneously injected with 0.05 mu C / sup 137/Cs/ g body weight. Simultaneously, 1.0 mg of DOCA (as a single dose or daily administration for 3 days), 12.5 mg of cortisone, or 0.1 ml of 10% solution of CsCl was intramuscularly administered to these rats. Radioassays of muscle, testis, liver, and spleen showed that the CsCl and the steroids decreased the deposition of /sup 137/Cs. The urinary and fecal excretion rates of /sup 137/Cs increased, in general, as the total amount of /sup 137/Cs deposited in the organs increased. (BBB)
- Research Organization:
- Kumamoto Univ., Japan
- NSA Number:
- NSA-18-017443
- OSTI ID:
- 4058044
- Journal Information:
- Kumamoto Medical Journal (Japan), Journal Name: Kumamoto Medical Journal (Japan) Vol. Vol: 15; ISSN KUMJA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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