FORMATION OF ELONGATED FORMS OF E. COLI UNDER CONTINUOUS GAMMA IRRADIATION

Journal Article · Wed Jan 01 04:00:00 EST 1964 · Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.)

OSTI ID:4056751

Zhestyanikov, B D

Observations on E. coli in a phase-contrast apparatus showed considerable numbers of elongated and filament forms in cultures cultivated with sub-bacteriostatic concentrations of erythromycin (25 to 30 mu g/ml) or at 46 deg C for 18 hr under continuous gamma irradiation. These abnormal cells seldom appeared after several generations without gamma irradiation. In two of the strains the elongated forms had up to 30 to 80 nuclei, and in another, up to ten nuclei per form. With appearance of the elongated forms the radiation resistance of the cultures increased. The dose dependence curve was S-shaped. This S shape is related to the accumulation of large numbers of elongated and undivided forms, although the correlation does not always exist. Other factors can also result in radiation resistance, and the factor causing inhibition of cell division without stopping growth is considered the factor that results in increased radiation resistance. (TTT)

• Research Organization: Inst. of Cytology, Leningrad
• NSA Number: NSA-18-017582
• OSTI ID: 4056751
• Journal Information: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.), Journal Name: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.) Vol. Vol: 4; ISSN RADOA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ANTIBIOTICS
BACTERIA
BIOLOGY AND MEDICINE
CELL NUCLEI
DIAGRAMS
ERYTHROMYCIN
ESCHERICHIA COLI
GAMMA RADIATION
GENETICS
IRRADIATION
MITOSIS
MUTATIONS
NUCLEIC ACIDS
RADIATION EFFECTS
RADIOSENSITIVITY
REPRODUCTION
SUSPENSIONS
TEMPERATURE
VARIATIONS