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NONRANDOM DISTRIBUTION OF LETHALS INDUCED BY TRITIATED THYMIDINE IN DROSOPHILA MELANOGASTER

Journal Article · · Genetics (U.S.)
OSTI ID:4050541
Mutations were induced in Drosophila males by tritiated thymidine fed to larvae or injected into adults. Radioautographs of testes of treated males demonstrated a correlation between the occurrence of mutations and the presence of labeled sperna bundles. In addition to the presence of sex-linked recessive lethals, dominant lethals were also measureable. Mapping of the induced sex- linked recessive lethals disclosed a nonrandom distribution which differed from reported distributions of mutations induced by x rays and gamma rays. Distribution of mutations induced by H/sup 3/T appears to reflect the varying frequency with which thymine bases occur along the lengih of the Drosophila X chromosome. (auth)
Research Organization:
City of Hope Medical Center, Duarte, Calif.
NSA Number:
NSA-18-017521
OSTI ID:
4050541
Journal Information:
Genetics (U.S.), Journal Name: Genetics (U.S.) Vol. Vol: 49; ISSN GENTA
Country of Publication:
Country unknown/Code not available
Language:
English

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