STUDIES OF THE INTESTINAL ABSORPTION OF $sup 59$Fe IN PATIENTS IRRADIATED IN THE ABDOMINO-PELVIC REGION

Journal Article · Thu Aug 01 00:00:00 EDT 1963 · Nuntius Radiol.

OSTI ID:4050232

Palma, L D

In continuing research on the functional changes of the small intestine during therapeutic irradiation, the intestinal absorption of the /sup 59/Fe and 18 patients irradiated on the abdomino-pelvic region was studied. In order to evalunte the avidity of the tissues for the metal the plasmatic T1/2 of a dose of /sup 59/Fe injected endovenously was simultaneously determined in these patients. The statistical elaboration of the results obtained permitted definition of a mean behaviour characterized by a decrease of the intestinal absorption and by a lengihening of the T1/2 of the /sup 59/Fe in the middle of the cycle of treatment, as well as by an increase of the absorption and an abbreviation of the T1/2 at the end of it. It was concluded that these results may be due either to an alteration of the intestinal wall which would decrease in the second part of the treatment, or to changes of the erythropoietic activity during the irradiation. (auth)

• Research Organization: Universita, Florence
• NSA Number: NSA-18-017562
• OSTI ID: 4050232
• Journal Information: Nuntius Radiol., Journal Name: Nuntius Radiol. Vol. Vol: 29
• Country of Publication: Country unknown/Code not available
• Language: Italian

Related Subjects

BIOLOGY AND MEDICINE
BLOOD CIRCULATION
BLOOD FORMATION
BLOOD PLASMA
BLOOD VESSELS
DIFFUSION
ERYTHROCYTES
HALF-LIFE
INTESTINE
IRON 56
IRRADIATION
MAN
METABOLISM
PHYSIOLOGY
QUANTITATIVE ANALYSIS
QUANTITY RATIO
RADIATION EFFECTS
RADIATION INJURIES
RADIOSENSITIVITY
RADIOTHERAPY
STATISTICS
TISSUES
VARIATIONS