FUNDAMENTAL STUDY ON THE COMBINED USE OF RADIATION AND CHEMICALS TO INTENSIFY THE ACTION OF RADIATION. I. EFFECT OF SEVERAL CHEMICAL AGENTS ON X-IRRADIATION IN VITRO

Journal Article · Thu Jan 01 04:00:00 EST 1959 · Kitakanko Igaku

OSTI ID:4048480

Mochizuki, H

Five days after the transplantation of Yoshida ascites sarcoma into the peritoneal cavity of Wistar strain rats, the ascites fluid was extracted and irradiated. There was no intensifying effect when the combination of x ray and monoiodoacetate was used. Rather, some protective effect was found. The combined use of x ray and 2 x 10/sup -//sup 3/ M of cysteine caused neither intensifying action nor protective effect. The use of 2 x 10/sup -//sup 3/ M of DL-glutamic acid alone caused no cancerous effects; however, an intensifying action was seen when it was used in combination with radiation. Neither indirect action nor effect of chemicals resulted in the subcutaneous tumors transplanted 2.5 cm apant. (Absts. Japan. Med., No. 7, 1960.)

• Research Organization: Gunma Univ., Maebashi, Japan
• NSA Number: NSA-15-022054
• OSTI ID: 4048480
• Journal Information: Kitakanko Igaku, Journal Name: Kitakanko Igaku Vol. Vol: 9
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ACETATES
ACIDS
AMINO ACIDS
BIOLOGY AND MEDICINE
CARCINOGENESIS
CHEMICALS
CYSTEINE
GLUTAMIC ACID
IODINE COMPOUNDS
IRRADIATION
RADIATION PROTECTION
RATS
TRANSPLANTS
TUMORS
X RADIATION