Impairment of Erythropoiesis by Irradiation
Investigations indicated that erythropoietin induces erythrocyte production by stimulating differentiation of primitive cells of the reticulum. An orderly wave of erythropoiesis was observed to sweep through the reticulum of mice with transfusion-induced polycythemia in response ot a single injection of erythropoietin. Whole-body x irradiation caused reduction in the incorporation of Fe59 in the red cells of polycythemic mice given a single injection of erythropoietin. (C.H.)
- Research Organization:
- Univ. of Chicago
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-15-023319
- OSTI ID:
- 4041012
- Journal Information:
- Nature (London), Journal Name: Nature (London) Journal Issue: 4780 Vol. 190; ISSN 0028-0836
- Publisher:
- Nature Publishing Group
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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