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RADIATION PROTECTION OF MICE WITH BONE MARROW AND SPLEEN PRESERVED AT LOW TEMPERATURE USING POLYVINYLPYRROLIDONE

Journal Article · · Blood (U.S.)
OSTI ID:4036504

Previously reported results of low-temperature preservation of bone marrow with 10% polyvinylpyrrolidone (PVP) were re-evaluated on the radiation protection basis. The lethally irradiated mice show 80% recovery after the transplantation of PVP-preserved isologous bone marrow, when compared to the recovery rate of the mice receiving fresh marrow. Slightly higher recovery resulted from the marrow preserved with glycerol. The spleen cells preserved with PVP aiso induce high recovery in irradiated mice. (auth)

Research Organization:
Presbyterian Medical Center, San Francisco, Calif.
NSA Number:
NSA-18-019778
OSTI ID:
4036504
Journal Information:
Blood (U.S.), Journal Name: Blood (U.S.) Vol. Vol: 23; ISSN BLOOA
Country of Publication:
Country unknown/Code not available
Language:
English