EXPERIMENTS ON PHOTOCHEMICAL AMINE FORMATION (in German)
Journal Article
·
· Strahlentherapie (West Germany)
OSTI ID:4018911
It is shown that phenylalanine, tryptophan, and tyrosine in aqueous solutions are decarboxylized to phenylethylamine, tryptamine, and tyramine by uv- irradiation: therefore, production of dopamine in uv-irradiated dioxyphenylalanine solutions is considered probable. Therefore, not only vasodilating (histamine, serotonine) but also vasoconstrictor amines are produced by the photochemical amino acid decomposition. A substance in its effect similar to histamine is formed in addition to tyramine in uv-irradiated tyrosine solutions. Its chemical nature is unknown. The photochemical production of amines is increased by oxygen, reducing substances, and H/sub 2/O/sub 2/. It is assumed that it is caused not only directly by energy absorption but also indirectiy by the influence of OH- radicals. The radiobiological importance of the results is discussed. (auth)
- Research Organization:
- Heiligenberg-Institut, Ger. and Universitat, Freiburg i. B.
- NSA Number:
- NSA-18-020081
- OSTI ID:
- 4018911
- Journal Information:
- Strahlentherapie (West Germany), Journal Name: Strahlentherapie (West Germany) Vol. Vol: 123; ISSN STRAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- German
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