NEUROSPORA MUTANTS LACKING ORNITHINE TRANSCARBAMYLASE
Journal Article
·
· Genetics (U.S.)
OSTI ID:4018805
Mutants lacking ornithine transcarbamylase, the enzyme which couples ornlthine to carbamyl phosphate, were isolated by two methods: as suppressors of the class of pyr-3 mutants displaying in vitro aspartic transcarbamylase activity, and by the filtration and selective plating technic, using conidia of a suppressor mutation, s. This strain suppresses, among other mutants, the class of pyr-3 mutants referred to above. The enzymatic phenotypes of these mutants are described and, although infertility makes it difficult to prove allelism, genetic analyses indicate that all of the mutants studied are located near arg-5 on linkage group II. (auth)
- Research Organization:
- Rice Univ., Houston, Tex.
- NSA Number:
- NSA-18-019621
- OSTI ID:
- 4018805
- Journal Information:
- Genetics (U.S.), Vol. Vol: 49; Other Information: Orig. Receipt Date: 31-DEC-64
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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OSTI ID:4018805
Prenatal monitoring in a family at high risk for ornithine transcarbamylase (OTC) deficiency: A new mutation of an A-to-C transversion in position +4 of intron 1 of the OTC gene that is likely to abolish enzyme activity
Journal Article
·
Fri Aug 23 00:00:00 EDT 1996
· American Journal of Medical Genetics
·
OSTI ID:4018805
Enzymatic synthesis of (N-13) or (C-11) carbamyl phosphate and their use for labeling metabolites of the urea cycle and the pyrimidine nucleotide pathway
Conference
·
Sun Jan 01 00:00:00 EST 1984
· J. Nucl. Med.; (United States)
·
OSTI ID:4018805
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