Complementation and Recombination Among PYR-3 Heteroalleles of Neurospora Crassa

Journal Article · Thu Mar 01 04:00:00 EST 1962 · Proceedings of the National Academy of Sciences of the United States of America

DOI:https://doi.org/10.1073/pnas.48.3.348· OSTI ID:4797313

Woodward, V. W.

Comparison between a genetic and a complementation map of the pyrimidine- 3 locus of Neurospora is presented. The exceptions to co-linearity are numerous. Several pairs of mutants shown to be allelic by one criterion are nonallelic by the other criterion; strikingly, homoallelic multisite mutants complement. One possible explanation of this finding is discussed. The complementation pattern of one mutant can be changed by ultraviolet induction of a mutation that resembles an intragenic-suppressor. The new mutation was not separated from the pyr-3 locus in more than 750 progeny tested thus far. It is specific for the KS- 23-KS-43 combination, and it does not change either the reverse mutation rate of KS-23 or the map distances between KS-23 and other pyr-3 mutants.

• Research Organization: Rice Univ., Houston, Tex.
• Sponsoring Organization: USDOE
• NSA Number: NSA-16-012858
• OSTI ID: 4797313
• Journal Information: Proceedings of the National Academy of Sciences of the United States of America, Journal Name: Proceedings of the National Academy of Sciences of the United States of America Journal Issue: 3 Vol. 48; ISSN 0027-8424
• Publisher: National Academy of Sciences, Washington, DC (United States)
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
FUNGI
GENETICS
MUTATIONS
NEUROSPORA
ULTRAVIOLET RADIATION