THE INFLUENCE OF S-$beta$-AMINOETHYLISOTHIURONIUM/center dot/Br/center dot/ HBr (aet), CYSTEAMINE (MEA) AND THIOCTIC ACID ON THE WALKER-CARCINOMA WITH FRACTIONATED LOCAL IRRADIATION

Journal Article · Tue Jan 01 04:00:00 EST 1963 · Radiobiol. Radiotherap.

OSTI ID:4016281

Huber, R

AET, MEA, and thioctic-acid given before the fractionated local irradiation of the Walker carcinoma of rats do not have any radioprotective effect. Furthermore AET and MEA seem to increase the radiation effect on the tumor. The radioprotective effect of MEA known in single irradiation is also removed with the fractionated whole-body irradiation as is shown by experiments on animals protected with MEA. Regarding the present literature the results show, that the SH-compounds AET, MEA and thioctic acid are not able to increase the radiobiological sensitivity between tumor and normal tissue as is desired in therapy. (auth)

• Research Organization: Robert-Roessle Clinic, German Academy of Sciences, Berlin
• NSA Number: NSA-18-019798
• OSTI ID: 4016281
• Journal Information: Radiobiol. Radiotherap., Journal Name: Radiobiol. Radiotherap. Vol. Vol: 4
• Country of Publication: Country unknown/Code not available
• Language: German

Related Subjects

AET
AMINES
ANIMAL CELLS
BIOLOGY AND MEDICINE
BODY
CANCER
EFFICIENCY
ETHYL RADICALS
IRRADIATION
MEA
ORGANIC ACIDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
RADIATION EFFECTS
RADIATION PROTECTION
RADIOBIOLOGY
RADIOSENSITIVITY
RATS
THIOCTIC ACID
TUMORS
VARIATIONS
WALKER CARCINOMA