STUDIES ON THE DISTRIBUTION AND PHOSPHATE TURNOVER OF THE ACID-SOLUBLE PHOSPHORUS COMPOUNDS IN VARIOUS NORMAL AND NEOPLASTIC TISSUES OF RATS. II. COMPARISON OF THE CHROMATOGRAMS OBTAINED WITH VARIOUS TISSUES INCLUDING TUMOURS (ENGLISH TEXT)
Journal Article
·
· Journal of Biochemistry (Tokyo) (Japan)
OSTI ID:4011281
Using a modified semi-micro gradient elution method of chromatography, the distribution of the acid-soluble nucleotides in various normal and neoplastic tissues of rats was compared and the variations of the distribution are described. The distribution and phosphate turnover of the acid-soluble phosphorus compounds were also studied by intraperitoneal injection of P/sup 32/ followed by the chromatographic analysis. The distribution patterns of nucleotides and radioactivity in liver, muscle, heart, lung, thymus, spleen, testicles, brain, fetal liver, and experimental hepatomas are illustrated and the differences between these tissues were pointed out. The characteristics of the experimental hepatoma tissue as compared with the normal liver tissue are as follows: The concentration of oxidized DPN was low; the incorporation of P/sup 32/ inorganic phosphate into glucose 6-phosphate and L- alpha -glycerophosphate was absent or, if any, very low; radioactivity of inorganic phosphate in the total acid-soluble radioactivity was extraordinarily high as compared with other tissues besides the liver tissue. (Abstr. Japan Med., 1: No. 9, 1961)
- Research Organization:
- Tokyo Univ.
- NSA Number:
- NSA-15-025841
- OSTI ID:
- 4011281
- Journal Information:
- Journal of Biochemistry (Tokyo) (Japan), Journal Name: Journal of Biochemistry (Tokyo) (Japan) Vol. Vol: 47; ISSN JOBIA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
Similar Records
STUDIES ON THE DISTRIBUTION AND PHOSPHATE TURNOVER OF THE ACID-SOLUBLE PHOSPHORUS COMPOUNDS IN VARIOUS NORMAL AND NEOPLASTIC TISSUES OF RATS. I. A SEMI-MICRO GRADIENT ELUTION CHROMATOGRAPHY WITH DOWEX FORMATE AND IDENTIFICATION OF SOME PHOSPHATE ESTERS ON THE CHROMATOGRAM (ENGLISH TEXT)
DIFFERENCES IN RADIOSENSITIVITY AND RECOVERY FROM THE EFFECTS OF RADIATION BETWEEN TWO TYPES OF ASCITES HEPATOMA IN THE RAT
Affinity of $sup 253$Es for tumour tissue
Journal Article
·
Thu Dec 31 23:00:00 EST 1959
· Journal of Biochemistry (Tokyo) (Japan)
·
OSTI ID:4011448
DIFFERENCES IN RADIOSENSITIVITY AND RECOVERY FROM THE EFFECTS OF RADIATION BETWEEN TWO TYPES OF ASCITES HEPATOMA IN THE RAT
Journal Article
·
Wed Dec 31 23:00:00 EST 1958
· Nippon Igaku Hoshasen Gakkai Zasshi (Japan)
·
OSTI ID:4843765
Affinity of $sup 253$Es for tumour tissue
Journal Article
·
Wed Oct 31 23:00:00 EST 1973
· Nature (London) New Biol., v. 246, no. 149, pp. 23-25
·
OSTI ID:4430143