Biomedical magnetic resonance imaging and spectroscopy with laser polarized noble gases

Journal Article · Wed May 01 04:00:00 EDT 1996 · Bulletin of the American Physical Society

OSTI ID:394184

Welsh, R C; Rosen, M S; Coulter, K P; Chupp, T E; Swanson, S D; Agranoff, B W; Prince, M R ^[1]

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1. Univ. of Michigan, Ann Arbor, MI (United States)

In the past year, a great deal of attention has been drawn to the use of laser polarized noble gases to produce magnetic resonance images of rodent and human lungs. Initial demonstrations proved the principle that air space images can be produced with noble gases polarized to several percent. (The noble gas density is thousands of times greater than the proton polarization of order 10{sup {minus}5} at 2 Tesla.) The manifold motivations include improvement of pulmonary and circulatory diagnostic radiology techniques as well as study of physiological function including neurological response. The authors have undertaken a program of development and application of MR imaging and spectroscopy using laser polarized gases with several goals including development of techniques and technologies to facilitate research and eventual medical applications. This talk will describe this multi-disciplinary program combining laser and optical physics, magnetic resonance tomography, neurophysiology and medical science.

• OSTI ID: 394184
• Report Number(s): CONF-9605105--
• Journal Information: Bulletin of the American Physical Society, Journal Name: Bulletin of the American Physical Society Journal Issue: 3 Vol. 41; ISSN BAPSA6; ISSN 0003-0503
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
BLOOD CIRCULATION
HELIUM 3
IMAGES
LUNGS
MAGNETIC RESONANCE
POLARIZATION
TOMOGRAPHY
XENON 129