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Nuclear magnetic resonance imaging with hyper-polarized noble gases

Technical Report ·
DOI:https://doi.org/10.2172/534499· OSTI ID:534499

This is the final report of a six-month, Laboratory Directed Research and Development (LDRD) project at Los Alamos National Laboratory (LANL). The nuclei of noble gases can be hyper polarized through a laser-driven spin exchange to a degree many orders of magnitude larger than that attainable by thermal polarization without requiring a strong magnetic field. The increased polarization from the laser pumping enables a good nuclear magnetic resonance (NMR) signal from a gas. The main goal of this project was to demonstrate diffusion-weighted imaging of such hyper-polarized noble gas with magnetic resonance imaging (MRI). Possible applications include characterizing porosity of materials and dynamically imaging pressure distributions in biological or acoustical systems.

Research Organization:
Los Alamos National Lab., NM (United States)
Sponsoring Organization:
USDOE Assistant Secretary for Human Resources and Administration, Washington, DC (United States)
DOE Contract Number:
W-7405-ENG-36
OSTI ID:
534499
Report Number(s):
LA-UR--97-3510; ON: DE98000087
Country of Publication:
United States
Language:
English

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