Microbial conversion of glycerol to 1,3-propanediol
- National Research Institute for Biotechnology, Braunschweig (Germany)
Glycerol is a byproduct from the soap and detergent industry and possibly from future biodiesel plants. The conversion of glycerol to 1,3-propanediol (PD) is of industrial interest due to the potential use of PD for the synthesis of polyesters. We have been studying the microbial conversion of glycerol to PD with work ranging from strain isolation, medium optimization, pathway analysis, product formation kinetics and growth modeling, downstream processing and reactor scale-up (up to 2000 1). PD yields of nearly 100% of the theoretical maximum (0.72 mol/mol glycerol) and final product concentrations of about 65 g/l were achieved with both Klebsiella pneumoniae and Clostridium butyricum. In addition to summarizing our experimental results the advances of bioconversion of glycerol will be reviewed in this presentation, with emphasis on discussing further research and development needs in this area. Results of process engineering and cost analysis will also be presented.
- OSTI ID:
- 370940
- Report Number(s):
- CONF-960376--
- Country of Publication:
- United States
- Language:
- English
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