Main and interaction effects of acetic acid, furfural, and p-hydroxybenzoic acid on growth and ethanol productivity of yeasts
- Univ. of Lund (Sweden)
The influence of the factors acetic acid, furfural, and p-hydroxybenzoic acid on the ethanol yield (Y{sub EtOH}) of Saccharomyces cerevisiae, bakers` yeast, S. cerevisiae ATCC 96581, and Candida shehatae NJ 23 was investigated using a 2{sup 3}-full factorial design with 3 centerpoints. The results indicated that acetic acid inhibited the fermentation by C. shehatae NJ 23 markedly more than by bakers` yeast, whereas no significant difference in tolerance towards the compounds was detected between the S. cerevisiae strains. Furfural and the lignin derived compound p-hydroxybenzoic acid did not affect any of the yeasts at the cell mass concentration used. The results indicated that the linear model was not adequate to describe the experimental data. Based on the results from the 2{sup 3}-full factorial experiment, an extended experiment was designed based on a central composite design to investigate the influence of the factors on the specific growth rate ({mu}), biomass yield (Y{sub x}), volumetric ethanol productivity (Q{sub EtOH}), and Y{sub EtOH}. Bakers` yeast was chosen in the extended experiment due to its better tolerance towards acetic acid, which makes it a more interesting organism for use in industrial fermentations of lignocellulosic hydrolysates.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 347678
- Journal Information:
- Biotechnology and Bioengineering, Journal Name: Biotechnology and Bioengineering Journal Issue: 1 Vol. 63; ISSN BIBIAU; ISSN 0006-3592
- Country of Publication:
- United States
- Language:
- English
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