The CEPH consortium linkage map of human chromosome 13

Journal Article · Sat May 01 00:00:00 EDT 1993 · Genomics

DOI:https://doi.org/10.1006/geno.1993.1215· OSTI ID:28976

Bowcock, A M; Barnes, R I ^[1]; Gerken, S C; Leppert, M ^[2]; Shiang, R ^[3]; Jabs, E W; Warren, A C; Antonarakis, S ^[4]; Retief, A E ^[5]; Vergnaud, G ^[6]

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1. Univ. of Texas Southwestern Medical Center, Dallas, TX (United States)
2. Univ. of Utah School of Medicine, Salt Lake City, UT (United States)
3. Univ. of Iowa, Iowa City, IA (United States)
4. Johns Hopkins School of Medicine, Baltimore, MD (United States)
5. Univ. of Stellenbosch, Tygerberg (South Africa)
6. Centre d`Etudes du Bouchet, Vert le Petit (France); and others

The CEPH consortium map of chromosome 13 is presented. This map contains 59 loci defined by genotypes generated from CEPH family DNAs with 94 different probe and restriction enzyme combinations contributed by 9 laboratories. A total of 25 loci have been placed on the map with likelihood support of at least 1000:1. The map extends from loci in the centromeric region of chromosome 13 to the terminal band of the long arm. Multipoint linkage analyses provided estimates that the male, female, and sex-averaged maps extend for 158, 203, and 178cM respectively. The largest interval is 24 cM and is between D13Z1 (alphaRI) and ATP1AL1. The mean genetic distance between the 25 uniquely placed loci is 7 cM. 76 refs., 3 figs., 5 tabs.

• OSTI ID: 28976
• Journal Information: Genomics, Vol. 16, Issue 2; Other Information: PBD: May 1993
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
HUMAN CHROMOSOME 13
GENETIC MAPPING
BIOLOGICAL MARKERS