The CEPH consortium linkage map of human chromosome 2

Journal Article · Mon Nov 30 23:00:00 EST 1992 · Genomics; (United States)

DOI:https://doi.org/10.1016/S0888-7543(05)80129-6· OSTI ID:6758576

Spurr, N K; Cox, S; Bryant, S P ^[1]; Attwood, J ^[2]; Shields, D C ^[3]; Steinbrueck, T; Donis-Keller, H ^[4]; Jenkins, T ^[5]; Murray, J C ^[6]; Kidd, K K ^[7]

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1. Human Genetic Resources Unit, Herts (United Kingdom)
2. Univ. College London (United Kingdom)
3. Princess Anne Hospital, Southampton (United Kingdom)
4. Washington Univ. School of medicine, St. Louis, MO (United States)
5. Univ. of Witwatersrand, Johannesburg (South Africa)
6. Univ. of Iowa, Iowa City, IA (United States)
7. Yale Univ. School of Medicine, New Haven, CT (United States); and others

This paper describes the Centre d'Etude du Polymorphisme Humain (CEPH) consortium linkage map of chromosome 2. The map contains 36 loci defined by genotyping generated from the CEPH family DNAs. A total of 73 different markers were typed by 14 contributing laboratories; of these, 36 loci are ordered on the map with likelihood support of at least 1000:1. Markers are placed along the length of the chromosome but no markers were available to anchor the map at either telomere or the centromere. Multilocus linkage analysis has produced male, female, and sex-averaged maps extending for 261, 430, and 328 cM, respectively. The sex-averaged map contains five intervals greater than 15 cM and the mean genetic distance between the 36 uniquely placed loci is 9.1 cM. 25 refs., 2 figs., 4 tabs.

• OSTI ID: 6758576
• Journal Information: Genomics; (United States), Journal Name: Genomics; (United States) Vol. 14:4; ISSN 0888-7543; ISSN GNMCEP
• Country of Publication: United States
• Language: English

Related Subjects

550400* -- Genetics
59 BASIC BIOLOGICAL SCIENCES
BIOLOGICAL MARKERS
CHROMOSOMES
GENETIC MAPPING
HUMAN CHROMOSOME 2
HUMAN CHROMOSOMES
MAPPING