The toxic milk mutation, tx, which results in a condition resembling Wilson disease in humans, is linked to mouse chromosome 8
- Univ. of Massachusetts, Amherst, MA (United States)
Litters produced by females homozygous for the toxic milk mutation, tx/tx, display a syndrome that includes poor growth, hypopigmentation, tremors, and death before 2 weeks of age. These features, consistent with copper deficiency, are attributed to failure in fetal hepatic copper accumulation. Here we report the chromosomal linkage of this mutation. 5 refs., 1 tab.
- OSTI ID:
- 258298
- Journal Information:
- Genomics, Journal Name: Genomics Journal Issue: 2 Vol. 29; ISSN GNMCEP; ISSN 0888-7543
- Country of Publication:
- United States
- Language:
- English
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