A linkage map of human chromosome 14, including 13 gene loci

Journal Article · Thu Sep 15 04:00:00 EDT 1994 · Genomics

DOI:https://doi.org/10.1006/geno.1994.1508· OSTI ID:255133

Cox, D W; Billingsley, G; Nguyen, V T.T. ^[1]

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1. The Hospital for Sick Children, Ontario (Canada)

The long arm of human chromosome 14 (14q), an acrocentric chromosome, is estimated to be approximately 93 Mb in length. Genetic maps published to date have included mostly random DNA markers. The map presented here includes 13 genes, as well as 29 random DNA segments, based on typing of the CEPH families. The map has been placed in context with other published maps. The resulting map of 42 loci has markers on average 5 cM apart and has a total length of 163 cM. The map order differs in the telomeric region from that of other maps previously published. 14q has homology, throughout approximately half its length, with mouse chromosome 12 and has a proximal region of homology with mouse chromosome 14. 35 refs., 2 figs., 5 tabs.

• OSTI ID: 255133
• Journal Information: Genomics, Journal Name: Genomics Journal Issue: 2 Vol. 23; ISSN 0888-7543; ISSN GNMCEP
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
DNA HYBRIDIZATION
GENETIC MAPPING
HUMAN CHROMOSOME 14
RFLPS