Packaging “vegetable oils”: Insights into plant lipid droplet proteins

Cai, Yingqi; Horn, Patrick J.

doi:10.1093/plphys/kiae533

Packaging “vegetable oils”: Insights into plant lipid droplet proteins

Journal Article · Wed Nov 20 04:00:00 EST 2024 · Plant Physiology (Bethesda)

DOI:https://doi.org/10.1093/plphys/kiae533· OSTI ID:2516764

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Abstract

Plant neutral lipids, also known as “vegetable oils”, are synthesized within the endoplasmic reticulum (ER) membrane and packaged into subcellular compartments called lipid droplets (LDs) for stable storage in the cytoplasm. The biogenesis, modulation, and degradation of cytoplasmic LDs in plant cells are orchestrated by a variety of proteins localized to the ER, LDs, and peroxisomes. Recent studies of these LD-related proteins have greatly advanced our understanding of LDs not only as steady oil depots in seeds but also as dynamic cell organelles involved in numerous physiological processes in different tissues and developmental stages of plants. In the past 2 decades, technology advances in proteomics, transcriptomics, genome sequencing, cellular imaging and protein structural modeling have markedly expanded the inventory of LD-related proteins, provided unprecedented structural and functional insights into the protein machinery modulating LDs in plant cells, and shed new light on the functions of LDs in nonseed plant tissues as well as in unicellular algae. Here, we review critical advances in revealing new LD proteins in various plant tissues, point out structural and mechanistic insights into key proteins in LD biogenesis and dynamic modulation, and discuss future perspectives on bridging our knowledge gaps in plant LD biology.

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Sponsoring Organization:: USDOE

Grant/Contract Number:: SC0016536

OSTI ID:: 2516764

Alternate ID(s):: OSTI ID: 2478168

Journal Information:: Plant Physiology (Bethesda), Journal Name: Plant Physiology (Bethesda) Journal Issue: 2 Vol. 197; ISSN 0032-0889

Publisher:: Oxford University PressCopyright Statement

Country of Publication:: United States

Language:: English

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