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Palladium-mediated C-C bond forming reactions: Cross-coupling reactions of organozinc and organotin reagents with purinones and triazines

Conference ·
OSTI ID:250138
; ;  [1]
  1. Schering-Plough Research Institute, Kenilworth, NJ (United States)

Palladium-mediated cross coupling reactions of organozinc and organotin reagents were used to form C-C bonds on heterocyclic substrates (8-bromopurin-6-ones and monochloro-1,3,5-triazines). These reactions represent the first examples of such coupling reactions on the above heterocyclic systems and they offer new ways to introduce a variety of carbon substituents into purinones and triazines.

OSTI ID:
250138
Report Number(s):
CONF-9508100--
Country of Publication:
United States
Language:
English