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Palladium catalyzed synthesis of allenes and disubstituted benzene from conjugated enynes

Conference ·
OSTI ID:250102

It has been found that Pd(0) - bidentate phosphine complex effectively catalyses the addition of CN-containing pronucleophiles 2 to conjugated enynes 1 leading with good to quantitative yields to the corresponding allenes 3. The role of nature of substituents in the enynes 1 and pronucleophiles 2, as well as type of bidentate phosphine ligands in the reaction mentioned will be discussed. In the presence of catalytic amounts of Pd(PPh{sub 3}){sub 4}, no addition of 2 to monosubstituted enynes 1 takes place instead dimerization reaction occurs afford 1,4-disubstituted aromatic compounds 4 in good yields.

OSTI ID:
250102
Report Number(s):
CONF-9508100--
Country of Publication:
United States
Language:
English

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