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Single Nucleotide Polymorphism Typing of Bacillus anthracis from Sverdlovsk Tissue

Journal Article · · Emerging Infectious Diseases
 [1];  [2];  [2];  [3];  [4];  [4];  [4];  [4];  [4];  [3];  [5];  [6]
  1. Los Alamos National Laboratory (LANL), Los Alamos, NM (United States); Northern Arizona Univ., Flagstaff, AZ (United States)
  2. Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
  3. Ibis Biosciences Inc., Carlsbad, CA (United States)
  4. Northern Arizona Univ., Flagstaff, AZ (United States)
  5. Los Alamos National Laboratory (LANL), Los Alamos, NM (United States); Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
  6. Los Alamos National Laboratory (LANL), Los Alamos, NM (United States); Northern Arizona Univ., Flagstaff, AZ (United States); Translational Genomics Research Institute, Phoenix, AZ (United States)
+ Show Author Affiliations
A small number of conserved canonical single nucleotide polymorphisms (canSNP) that define major phylogenetic branches for Bacillus anthracis were used to place a Sverdlovsk patient’s B. anthracis genotype into 1 of 12 subgroups. Reconstruction of the pagA gene also showed a unique SNP that defines a new lineage for B. anthracis.
Research Organization:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Organization:
USDOE
Grant/Contract Number:
AC52-07NA27344
OSTI ID:
2471160
Journal Information:
Emerging Infectious Diseases, Journal Name: Emerging Infectious Diseases Journal Issue: 4 Vol. 14; ISSN 1080-6040
Publisher:
Centers for Disease Control and Prevention (CDC)Copyright Statement
Country of Publication:
United States
Language:
English

References (13)

Anthrax molecular epidemiology and forensics: using the appropriate marker for different evolutionary scales journal September 2004
Genomics: Anthrax and the art of war (against ascertainment bias) journal January 2005
Phylogenetic discovery bias in Bacillus anthracis using single-nucleotide polymorphisms from whole-genome sequencing journal September 2004
Pathology of inhalational anthrax in 42 cases from the Sverdlovsk outbreak of 1979. journal March 1993
PCR analysis of tissue samples from the 1979 Sverdlovsk anthrax victims: The presence of multiple Bacillus anthracis strains in different victims journal February 1998
The Sverdlovsk anthrax outbreak of 1979 journal November 1994
Characterization of the variable-number tandem repeats in vrrA from different Bacillus anthracis isolates journal April 1997
Genetic Diversity in the Protective Antigen Gene ofBacillus anthracis journal April 1999
Strain-Specific Single-Nucleotide Polymorphism Assays for the Bacillus anthracis Ames Strain journal November 2006
Genetic Diversity in a Bacillus anthracis Historical Collection (1954 to 1988) journal June 2007
Molecular evolution and diversity in Bacillus anthracis as detected by amplified fragment length polymorphism markers. journal January 1997
Global Genetic Population Structure of Bacillus anthracis journal May 2007
Mass Spectrometry Provides Accurate Characterization of two Genetic Marker Types in Bacillus Anthracis journal October 2004

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Related Subjects

60 APPLIED LIFE SCIENCES
immunology
infectious diseases