Enzymatic Laser-Induced Graphene Biosensor for Electrochemical Sensing of the Herbicide Glyphosate

Johnson, Zachary T.; Jared, Nathan; Peterson, John K.; Li, Jingzhe; Smith, Emily A.; Walper, Scott A.; Hooe, Shelby L.; Breger, Joyce C.; Medintz, Igor L.; Gomes, Carmen; Claussen, Jonathan C.

doi:10.1002/gch2.202200057

Enzymatic Laser-Induced Graphene Biosensor for Electrochemical Sensing of the Herbicide Glyphosate

Journal Article · Tue Jul 26 04:00:00 EDT 2022 · Global Challenges

DOI:https://doi.org/10.1002/gch2.202200057· OSTI ID:2469932

Johnson, Zachary T. ^[1]; Jared, Nathan ^[1]; Peterson, John K. ^[1]; Li, Jingzhe ^[2]; Smith, Emily A. ^[2]; Walper, Scott A. ^[3]; Hooe, Shelby L. ^[4]; Breger, Joyce C. ^[3]; Medintz, Igor L. ^[3]; Gomes, Carmen ^[1]; ^[1]

Iowa State University, Ames, IA (United States)
Ames Laboratory, and Iowa State University, Ames, IA (United States)
U.S. Naval Research Laboratory, Washington, DC (United States)
U.S. Naval Research Laboratory, Washington, DC (United States); National Research Council, Washington, DC (United States)

Glyphosate is a globally applied herbicide yet it has been relatively undetectable in-field samples outside of gold-standard techniques. Its presumed nontoxicity toward humans has been contested by the International Agency for Research on Cancer, while it has been detected in farmers’ urine, surface waters and crop residues. Rapid, on-site detection of glyphosate is hindered by lack of field-deployable and easy-to-use sensors that circumvent sample transportation to limited laboratories that possess the equipment needed for detection. Herein, the flavoenzyme, glycine oxidase, immobilized on platinum-decorated laser-induced graphene (LIG) is used for selective detection of glyphosate as it is a substrate for GlyOx. The LIG platform provides a scaffold for enzyme attachment while maintaining the electronic and surface properties of graphene. The sensor exhibits a linear range of 10–260 µm, detection limit of 3.03 µm, and sensitivity of 0.991 nA µm^-1. The sensor shows minimal interference from the commonly used herbicides and insecticides: atrazine, 2,4-dichlorophenoxyacetic acid, dicamba, parathion-methyl, paraoxon-methyl, malathion, chlorpyrifos, thiamethoxam, clothianidin, and imidacloprid. Sensor function is further tested in complex river water and crop residue fluids, which validate this platform as a scalable, direct-write, and selective method of glyphosate detection for herbicide mapping and food analysis.

View Accepted Manuscript (DOE)

Research Organization:: Ames Laboratory (AMES), Ames, IA (United States)

Sponsoring Organization:: USDOE; National Science Foundation (NSF); USDA; Strategic Environmental Research and Development Program (SERDP)

Grant/Contract Number:: AC02-07CH11358

OSTI ID:: 2469932

Journal Information:: Global Challenges, Journal Name: Global Challenges Journal Issue: 9 Vol. 6; ISSN 2056-6646

Publisher:: WileyCopyright Statement

Country of Publication:: United States

Language:: English

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47 OTHER INSTRUMENTATION
biosensors
glycine oxidase
glyphosate
herbicides
laser-induced graphene
science & technology

Enzymatic Laser-Induced Graphene Biosensor for Electrochemical Sensing of the Herbicide Glyphosate

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