Toxicity of nonylphenol and nonylphenol ethoxylates to Ceriodaphnia
- ABC Labs., Columbia, MO (United States)
- Union Carbide, South Charleston, WV (United States)
The 7-day survival and reproduction toxicity test on Ceriodaphnia dubia was performed using Good Laboratory Practices procedures. The definitive GLP tests were preceded by range-finding tests with only nominal concentrations and by analytical method validation. Substances used were industrial-grade nonylphenol (CAS No. 84852-15-3) and its 1.5-mole ethoxylate (CAS No. 9016-45-9). Analysis was done by solvent extraction and HPLC. All work was done in glassware to minimize loss of test substances to surface adsorption. The NOEC values for NP and NPE{sub 1.5} were, respectively, 89 and 285/{micro}g/L. LC50 values (96 hour) were 276 and 1016/{micro}g/L, respectively. These results demonstrate that Ceriodaphnia are much less sensitive to these chemicals than are other aquatic organisms.
- OSTI ID:
- 244895
- Report Number(s):
- CONF-9511137--; ISBN 1-880611-03-1
- Country of Publication:
- United States
- Language:
- English
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