Manipulating Fermentation Pathways in the Hyperthermophilic Archaeon Pyrococcus furiosus for Ethanol Production up to 95°C Driven by Carbon Monoxide Oxidation

Lipscomb, Gina L.; Crowley, Alexander T.; Nguyen, Diep M.  N.; Keller, Matthew W.; O’Quinn, Hailey C.; Tanwee, Tania N.  N.; Vailionis, Jason L.; Zhang, Ke; Zhang, Ying; Kelly, Robert M.; Adams, Michael W.  W.; Cann, Isaac

doi:10.1128/aem.00012-23

Manipulating Fermentation Pathways in the Hyperthermophilic Archaeon Pyrococcus furiosus for Ethanol Production up to 95°C Driven by Carbon Monoxide Oxidation

Journal Article · Wed Jun 28 00:00:00 EDT 2023 · Applied and Environmental Microbiology

DOI:https://doi.org/10.1128/aem.00012-23· OSTI ID:2422078

Lipscomb, Gina L. ^[1]; Crowley, Alexander T. ^[2]; Nguyen, Diep M. N. ^[2]; Keller, Matthew W. ^[2]; O’Quinn, Hailey C. ^[2]; Tanwee, Tania N. N. ^[2]; Vailionis, Jason L. ^[3]; Zhang, Ke ^[3]; ^[3]; ^[4]; ^[2]; Cann, Isaac

Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA; OSTI
Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA
Department of Cell and Molecular Biology, College of the Environment and Life Sciences, University of Rhode Island, Kingston, Rhode Island, USA
Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA

Previously, the highest temperature for biological ethanol production was 85°C. Here, we have engineered ethanol production at 95°C by the hyperthermophilic archaeonPyrococcus furiosus.

View Accepted Manuscript (DOE)

Research Organization:: Kent State Univ., Kent, OH (United States); Univ. of Georgia, Athens, GA (United States)

Sponsoring Organization:: USDOE Office of Science (SC)

Grant/Contract Number:: SC0022191; SC0022192

OSTI ID:: 2422078

Journal Information:: Applied and Environmental Microbiology, Journal Name: Applied and Environmental Microbiology Journal Issue: 6 Vol. 89; ISSN 0099-2240

Publisher:: American Society for MicrobiologyCopyright Statement

Country of Publication:: United States

Language:: English

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