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Online Cross-Linking of Peptides and Proteins during Contained-Electrospray Ionization Mass Spectrometry

Journal Article · · Analytical Chemistry
 [1];  [2];  [2]
  1. Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio43210, United States; OSTI
  2. Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio43210, United States

Not provided.

Research Organization:
The Ohio State Univ., Columbus, OH (United States)
Sponsoring Organization:
USDOE Office of Science (SC)
DOE Contract Number:
SC0022097
OSTI ID:
2422034
Journal Information:
Analytical Chemistry, Journal Name: Analytical Chemistry Journal Issue: 2 Vol. 95; ISSN 0003-2700
Publisher:
American Chemical Society (ACS)
Country of Publication:
United States
Language:
English

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Microdroplet Mass Spectrometry Enables Extremely Accelerated Pepsin Digestion of Proteins journal June 2021
Improving Laccase Catalyzed Cross-Linking of Whey Protein Isolate and Their Application as Emulsifiers journal January 2011
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A Simple Cross-Linking/Mass Spectrometry Workflow for Studying System-wide Protein Interactions journal July 2019
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Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies journal November 2017
Influence of Peptide Composition, Gas-Phase Basicity, and Chemical Modification on Fragmentation Efficiency:  Evidence for the Mobile Proton Model journal January 1996
Refining the Structural Model of a Heterohexameric Protein Complex: Surface Induced Dissociation and Ion Mobility Provide Key Connectivity and Topology Information journal November 2015
Hydrogen/Deuterium Exchange-Mass Spectrometry: A Powerful Tool for Probing Protein Structure, Dynamics and Interactions journal September 2007
The Cross-linking of Proteins with Glutaraldehyde and its use for the preparation of immunoadsorbents journal January 1969
Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry journal January 2020
Enzyme-Catalyzed Hydrolysis of Lipids in Immiscible Microdroplets Studied by Contained-Electrospray Ionization journal September 2021
Structural mass spectrometry comes of age: new insight into protein structure, function and interactions journal January 2019
Harmonizing structural mass spectrometry analyses in the mass spec studio journal August 2020
Peptide Cross-Linking at Ambient Surfaces by Reactions of Nanosprayed Molecular Cations journal August 2012
Ultrafast enzymatic digestion of proteins by microdroplet mass spectrometry journal February 2020
Improving mass spectrometry analysis of protein structures with arginine-selective chemical cross-linkers journal September 2019
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  • Scarff, Charlotte A.; Thalassinos, Konstantinos; Hilton, Gillian R.
  • Rapid Communications in Mass Spectrometry, Vol. 22, Issue 20 https://doi.org/10.1002/rcm.3737
journal October 2008
Gas-phase ion/ion chemistry for structurally sensitive probes of gaseous protein ion structure: Electrostatic and electrostatic to covalent cross-linking journal May 2021
Re-configurable, multi-mode contained-electrospray ionization for protein folding and unfolding on the millisecond time scale journal January 2017
Chemical Cross-linking and Mass Spectrometry for Protein Structural Modeling journal August 2003
Microdroplet fusion mass spectrometry for fast reaction kinetics journal March 2015
Protein Subunits Released by Surface Collisions of Noncovalent Complexes: Nativelike Compact Structures Revealed by Ion Mobility Mass Spectrometry journal March 2012
Chemical cross-linking and mass spectrometry to map three-dimensional protein structures and protein–protein interactions journal January 2006
Understanding chemical reactivity for homo‐ and heterobifunctional protein cross‐linking agents journal June 2013
Droplet Dynamics and Ionization Mechanisms in Desorption Electrospray Ionization Mass Spectrometry journal December 2006
Origin of Asymmetric Charge Partitioning in the Dissociation of Gas-Phase Protein Homodimers journal March 2003
Divide and conquer: cleavable cross-linkers to study protein conformation and protein–protein interactions journal October 2016

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