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Genetic heterogeneity of breast-ovarian cancer revisited

Journal Article · · American Journal of Human Genetics
OSTI ID:237452
 [1]; ;  [2]
  1. McGill Univ., Montreal (Canada)
  2. Univ. of Leiden (Netherlands); and others

We have recently reported the results of a linkage analysis of 145 breast-ovarian cancer families. Each family has three or more cases of early-onset breast cancer (age {le}60) or of ovarian cancer, and all families have at least one case of ovarian cancer (there were nine site-specific ovarian cancer families). Overall, we estimated that 76% of the families were linked to the BRCA1 locus. 5 refs., 1 tab.

OSTI ID:
237452
Journal Information:
American Journal of Human Genetics, Journal Name: American Journal of Human Genetics Journal Issue: 4 Vol. 57; ISSN AJHGAG; ISSN 0002-9297
Country of Publication:
United States
Language:
English

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