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Chromosomal localization of the {gamma}-glutamyl carboxylase gene at 2p12

Journal Article · · Genomics
;  [1];  [2]
  1. Univ. of California, San Francisco, CA (United States)
  2. Univ. of North Carolina, Chapel Hill, NC (United States); and others
We have used two complementary approaches to analyze the chromosomal location of the {gamma}-glutamyl carboxylase gene. The amplification of a carboxylase-specific genomic fragment by polymerase chain reaction (PCR) in a human-rodent hybrid cell mapping panel localized the gene to chromosome 2. Mapping by fluorescence in situ hybridization assigned the gene to p12 of chromosome 2. Our results indicate that the {gamma}-glutamyl carboxylase gene has a single locus in the human genome. 22 refs., 1 fig.
OSTI ID:
232728
Journal Information:
Genomics, Journal Name: Genomics Journal Issue: 3 Vol. 25; ISSN 0888-7543; ISSN GNMCEP
Country of Publication:
United States
Language:
English