Imaging plant metabolism in situ

Horn, Patrick J.; Chapman, Kent D.; Li-Beisson, ed., Yonghua

doi:10.1093/jxb/erad423

Imaging plant metabolism in situ

Journal Article · Fri Oct 27 00:00:00 EDT 2023 · Journal of Experimental Botany

DOI:https://doi.org/10.1093/jxb/erad423· OSTI ID:2323944

; ; Li-Beisson, ed., Yonghua

Abstract

Mass spectrometry imaging (MSI) has emerged as an invaluable analytical technique for investigating the spatial distribution of molecules within biological systems. In the realm of plant science, MSI is increasingly employed to explore metabolic processes across a wide array of plant tissues, including those in leaves, fruits, stems, roots, and seeds, spanning various plant systems such as model species, staple and energy crops, and medicinal plants. By generating spatial maps of metabolites, MSI has elucidated the distribution patterns of diverse metabolites and phytochemicals, encompassing lipids, carbohydrates, amino acids, organic acids, phenolics, terpenes, alkaloids, vitamins, pigments, and others, thereby providing insights into their metabolic pathways and functional roles. In this review, we present recent MSI studies that demonstrate the advances made in visualizing the plant spatial metabolome. Moreover, we emphasize the technical progress that enhances the identification and interpretation of spatial metabolite maps. Within a mere decade since the inception of plant MSI studies, this robust technology is poised to continue as a vital tool for tackling complex challenges in plant metabolism.

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Sponsoring Organization:: USDOE

Grant/Contract Number:: SC0000797; SC0016536

OSTI ID:: 2323944

Alternate ID(s):: OSTI ID: 2472307
OSTI ID: 2217565

Journal Information:: Journal of Experimental Botany, Journal Name: Journal of Experimental Botany Journal Issue: 6 Vol. 75; ISSN 0022-0957

Publisher:: Oxford University PressCopyright Statement

Country of Publication:: United Kingdom

Language:: English

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The genome of jojoba ( Simmondsia chinensis ): A taxonomically isolated species that directs wax ester accumulation in its seeds Sturtevant, Drew; Lu, Shaoping; Zhou, Zhi-Wei Science Advances, Vol. 6, Issue 11 https://doi.org/10.1126/sciadv.aay3240	journal	March 2020
The plant lipidome in human and environmental health Horn, P. J.; Benning, C. Science, Vol. 353, Issue 6305 https://doi.org/10.1126/science.aaf6206	journal	September 2016
Maldi-mass Spectrometry Imaging for Phytoalexins Detection in RD6 Thai Rice Komkleow, S.; Niyomploy, P.; Sangvanich, P. Applied Biochemistry and Microbiology, Vol. 57, Issue 4 https://doi.org/10.1134/S0003683821040074	journal	July 2021
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Aminopropyltransferases Involved in Polyamine Biosynthesis Localize Preferentially in the Nucleus of Plant Cells Belda-Palazón, Borja; Ruiz, Leticia; Martí, Esmeralda PLoS ONE, Vol. 7, Issue 10 https://doi.org/10.1371/journal.pone.0046907	journal	October 2012
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Advances in MALDI Mass Spectrometry Imaging Single Cell and Tissues Zhu, Xiaoping; Xu, Tianyi; Peng, Chen Frontiers in Chemistry, Vol. 9 https://doi.org/10.3389/fchem.2021.782432	journal	February 2022
In situ spatiotemporal mapping of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) inhibitor in pineapple (Ananas comosus) fruit tissue by MALDI mass spectrometry imaging Suarez, Angelica Faith L.; Juanillo, Angel Ann B.; Sison, Dave Clark D. Frontiers in Natural Products, Vol. 2 https://doi.org/10.3389/fntpr.2023.1160541	journal	April 2023
Comparing DESI-MSI and MALDI-MSI Mediated Spatial Metabolomics and Their Applications in Cancer Studies He, Michelle Junyi; Pu, Wenjun; Wang, Xi Frontiers in Oncology, Vol. 12 https://doi.org/10.3389/fonc.2022.891018	journal	July 2022
Microscopic Mass Spectrometry Imaging Reveals the Distribution of Phytochemicals in the Dried Root of Isatis tinctoria Nie, Li-Xing; Dong, Jing; Huang, Lie-Yan Frontiers in Pharmacology, Vol. 12 https://doi.org/10.3389/fphar.2021.685575	journal	June 2021
Sample Preparation for Mass Spectrometry Imaging of Plant Tissues: A Review Dong, Yonghui; Li, Bin; Malitsky, Sergey Frontiers in Plant Science, Vol. 7 https://doi.org/10.3389/fpls.2016.00060	journal	February 2016
Organic Acids: The Pools of Fixed Carbon Involved in Redox Regulation and Energy Balance in Higher Plants Igamberdiev, Abir U.; Eprintsev, Alexander T. Frontiers in Plant Science, Vol. 7 https://doi.org/10.3389/fpls.2016.01042	journal	July 2016
Visualizing Genotypic and Developmental Differences of Free Amino Acids in Maize Roots With Mass Spectrometry Imaging O’Neill, Kelly C.; Lee, Young Jin Frontiers in Plant Science, Vol. 11 https://doi.org/10.3389/fpls.2020.00639	journal	May 2020
Editorial: Amino Acids in Plants: Regulation and Functions in Development and Stress Defense Trovato, Maurizio; Funck, Dietmar; Forlani, Giuseppe Frontiers in Plant Science, Vol. 12 https://doi.org/10.3389/fpls.2021.772810	journal	October 2021
Grapevine leaf MALDI-MS imaging reveals the localisation of a putatively identified sucrose metabolite associated to Plasmopara viticola development Maia, Marisa; McCann, Andréa; Malherbe, Cédric Frontiers in Plant Science, Vol. 13 https://doi.org/10.3389/fpls.2022.1012636	journal	October 2022
A mass spectrometry imaging approach on spatiotemporal distribution of multiple alkaloids in Gelsemium elegans Wu, Zi-Han; Wang, Ruo-Zhong; Sun, Zhi-Liang Frontiers in Plant Science, Vol. 13 https://doi.org/10.3389/fpls.2022.1051756	journal	November 2022
Metabolic profiling, in-situ spatial distribution, and biosynthetic pathway of functional metabolites in Dendrobium nobile stem revealed by combining UPLC-QTOF-MS with MALDI-TOF-MSI Liu, Qingling; Huang, Yuan; Linghu, Chu Frontiers in Plant Science, Vol. 13 https://doi.org/10.3389/fpls.2022.1125872	journal	January 2023
Desorption Electrospray Ionization Mass Spectrometry Imaging Illustrates the Quality Characters of Isatidis Radix Nie, Li-Xing; Huang, Lie-Yan; Wang, Xin-Ping Frontiers in Plant Science, Vol. 13 https://doi.org/10.3389/fpls.2022.897528	journal	June 2022
Effective Mechanisms for Improving Seed Oil Production in Pennycress (Thlaspi arvense L.) Highlighted by Integration of Comparative Metabolomics and Transcriptomics Johnston, Christopher; García Navarrete, Leidy Tatiana; Ortiz, Emmanuel Frontiers in Plant Science, Vol. 13 https://doi.org/10.3389/fpls.2022.943585	journal	July 2022
Visualizing the distribution of flavonoids in litchi (Litchi chinenis) seeds through matrix-assisted laser desorption/ionization mass spectrometry imaging Liu, Yukun; Nie, Xiaofei; Wang, Jilong Frontiers in Plant Science, Vol. 14 https://doi.org/10.3389/fpls.2023.1144449	journal	February 2023
Analyzing Mass Spectrometry Imaging Data of 13C-Labeled Phospholipids in Camelina sativa and Thlaspi arvense (Pennycress) Embryos Romsdahl, Trevor B.; Kambhampati, Shrikaar; Koley, Somnath Metabolites, Vol. 11, Issue 3 https://doi.org/10.3390/metabo11030148	journal	March 2021
Mass Spectrometry Imaging Disclosed Spatial Distribution of Defense-Related Metabolites in Triticum spp. Righetti, Laura; Gottwald, Sven; Tortorella, Sara Metabolites, Vol. 12, Issue 1 https://doi.org/10.3390/metabo12010048	journal	January 2022
Complex Changes in Membrane Lipids Associated with the Modification of Autophagy in Arabidopsis Mugume, Yosia; Ding, Geng; Dueñas, Maria Metabolites, Vol. 12, Issue 2 https://doi.org/10.3390/metabo12020190	journal	February 2022
MALDI MSI and Raman Spectroscopy Application in the Analysis of the Structural Components and Flavonoids in Brassica napus Stem Krysa, Mikolaj; Susniak, Katarzyna; Kubas, Adrianna Metabolites, Vol. 13, Issue 6 https://doi.org/10.3390/metabo13060687	journal	May 2023
The Rhizosphere Microbiome of Ginseng Goodwin, Paul H. Microorganisms, Vol. 10, Issue 6 https://doi.org/10.3390/microorganisms10061152	journal	June 2022
Localization of Major Ephedra Alkaloids in Whole Aerial Parts of Ephedrae Herba Using Direct Analysis in Real Time-Time of Flight-Mass Spectrometry Yun, Nayoung; Kim, Hye Jin; Park, Sang Cheol Molecules, Vol. 26, Issue 3 https://doi.org/10.3390/molecules26030580	journal	January 2021
Study on the Distribution of Low Molecular Weight Metabolites in Mango Fruit by Air Flow-Assisted Ionization Mass Spectrometry Imaging Zhao, Deqing; Yu, Ping; Han, Bingjun Molecules, Vol. 27, Issue 18 https://doi.org/10.3390/molecules27185873	journal	September 2022
Localization Analysis of Multiple Vitamins in Dried Persimmon (Diospyros kaki) Using Matrix-assisted Laser Desorption/ionization Mass Spectrometry Imaging Shikano, Hitomi; Miyama, Yoko; Ikeda, Ryuzoh Journal of Oleo Science, Vol. 69, Issue 8 https://doi.org/10.5650/jos.ess20143	journal	January 2020

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