A nested case-control study of polychlorinated biphenyls, organochlorine pesticides, and thyroid cancer in the Janus Serum Bank cohort
Journal Article
·
· Environmental Research
- Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD (United States)
- Department of Research, Institute of Population-Based Cancer Research, Cancer Registry of Norway, Oslo (Norway)
- Department of Epidemiology, University of North Carolina Gillings School of Public Health, Chapel Hill, NC (United States)
- Division of Laboratory Sciences, Centers for Disease Control and Prevention, Atlanta, GA (United States)
- Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD (United States)
Highlights: • First study of pre-diagnostic organochlorine compounds in serum and thyroid cancer. • p,p′-DDE (DDT metabolite) inversely associated with thyroid cancer. • Birth cohort may be an effect modifier. • Some PCBs associated with thyroid cancer in youngest birth cohort. • Chlordane metabolites associated with thyroid cancer in youngest birth cohort. Polychlorinated biphenyls (PCBs) and organochlorine pesticides have been associated with altered thyroid hormone levels in humans, but their relationship with thyroid cancer is unknown.
- OSTI ID:
- 23105896
- Journal Information:
- Environmental Research, Journal Name: Environmental Research Vol. 165; ISSN ENVRAL; ISSN 0013-9351
- Country of Publication:
- United States
- Language:
- English
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