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Air pollution and the fetal origin of disease: A systematic review of the molecular signatures of air pollution exposure in human placenta

Journal Article · · Environmental Research
 [1]; ; ; ;  [1];  [1];  [2]
  1. Centre for Environmental Sciences, Hasselt University, Hasselt (Belgium)
  2. Unité de Recherche en Biologie Cellulaire (URBC) – Namur Research Institute for Life Sciences (Narilis), University of Namur (Belgium)
Fetal development is a crucial window of susceptibility in which exposure-related alterations can be induced on the molecular level, leading to potential changes in metabolism and development. The placenta serves as a gatekeeper between mother and fetus, and is in contact with environmental stressors throughout pregnancy. This makes the placenta as a temporary organ an informative non-invasive matrix suitable to investigate omics-related aberrations in association with in utero exposures such as ambient air pollution.
OSTI ID:
23105868
Journal Information:
Environmental Research, Journal Name: Environmental Research Vol. 166; ISSN ENVRAL; ISSN 0013-9351
Country of Publication:
United States
Language:
English

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