Clinical Utility of [{sup 18}F]FDG-PET /CT in Pericardial Disease
Journal Article
·
· Current Cardiology Reports (Print)
- Sungkyunkwan University School of Medicine, Division of Cardiology, Department of Medicine, Samsung Medical Center, Heart Vascular and Stroke Institute Imaging Center (Korea, Republic of)
- Sungkyunkwan University School of Medicine, Department of Nuclear Medicine and Molecular Imaging, Samsung Medical Center (Korea, Republic of)
- Mayo Clinic College of Medicine, Department of Cardiovascular Medicine (United States)
Identification of the etiology of pericardial disease is challenging because the accessibility to pericardial fluid and tissue is limited and there is a relatively low yield of fluid and tissue analysis. Pericardial disease is associated with various systemic diseases and is frequently a first manifestation of other systemic diseases. Detecting the cause of pericarditis and minimizing the subsequent inflammatory process can possibly prevent long-term complications. Purpose of Review: To review the clinical utility of [{sup 18}F]-2-deoxy-2-fluoro-D-glucose positron emission tomography/computed tomography ([{sup 18}F]FDG-PET/CT) in the diagnosis and treatment of pericardial disease. Recent Findings: [{sup 18}F]FDG-PET/CT can visualize the hypermetabolic tissues of both malignancy and inflammation. Distribution of [{sup 18}F]FDG-PET/CT uptake can provide information for neoplastic disease. If malignancy is ruled out, high uptake of pericardium is associated with active inflammation of the pericardium, and thus response to anti-inflammatory agents can also be predicted with [{sup 18}F]FDG-PET/CT imaging. Summary: [{sup 18}F]FDG-PET/CT can be helpful for diagnosing and establishing prognosis and for planning for anti-inflammatory treatment in pericardial disease.
- OSTI ID:
- 22929213
- Journal Information:
- Current Cardiology Reports (Print), Journal Name: Current Cardiology Reports (Print) Journal Issue: 9 Vol. 21; ISSN 1523-3782
- Country of Publication:
- United States
- Language:
- English
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