Cardiac Sarcoidosis

Journal Article · Sun Dec 15 04:00:00 EST 2019 · Current Cardiology Reports (Print)

DOI:https://doi.org/10.1007/S11886-019-1238-1· OSTI ID:22929140

Mankad, Pranav; Mitchell, Brian ^[1]; Birnie, David ^[2]; Kron, Jordana ^[1]

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1. Virginia Commonwealth University Medical Center, Pauley Heart Center (United States)
2. University of Ottawa Heart Institute (Canada)

Purpose of Review: In this state-of-the-art review, we highlight our current understanding of diagnosis, assessment, and management of cardiac sarcoidosis (CS), focusing on recently published data and expert consensus statement guidelines. Recent Findings: Academic interest in cardiac sarcoidosis research has increased over the past decade along with increased clinical awareness among clinicians. In 2014, the Heart Rhythm Society published the first expert consensus statement on diagnosing and managing arrhythmias associated with CS. Cardiac magnetic resonance has emerged as a valuable tool both for diagnosing CS and predicting risk of life-threatening ventricular arrhythmias based on burden of late gadolinium enhancement. Cardiac fluorodeoxyglucose-positron emission tomography now plays a role in diagnosis, risk stratification, and assessing response to immunosuppressive therapy. Summary: Collaborative, multidisciplinary research efforts are needed to further our understanding of this rare, complex disease. Two large multicenter prospective registries—the international Cardiac Sarcoidosis Consortium and the Canadian Cardiac Sarcoidosis Research Group—are enrolling patients to help provide insights into the natural history of the disease and current treatment strategies. Future research should focus on randomized controlled trials comparing different treatment strategies and identifying and testing novel therapeutic agents.

• OSTI ID: 22929140
• Journal Information: Current Cardiology Reports (Print), Journal Name: Current Cardiology Reports (Print) Journal Issue: 12 Vol. 21; ISSN 1523-3782
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CHEST
DIAGNOSIS
FLUORODEOXYGLUCOSE
GADOLINIUM
HEART
NMR IMAGING
PATIENTS
POSITRON COMPUTED TOMOGRAPHY
THERAPY