Replacing fish oil and astaxanthin by microalgal sources produced different metabolic responses in juvenile rainbow trout fed 2 types of practical diets

Zhu, Shanli; Portman, Mark; Cleveland, Beth M.; Magnuson, Andrew D.; Wu, Kun; Sealey, Wendy; Lei, Xin Gen

doi:10.1093/jas/skaa403

Replacing fish oil and astaxanthin by microalgal sources produced different metabolic responses in juvenile rainbow trout fed 2 types of practical diets

Journal Article · Mon Dec 21 00:00:00 EST 2020 · Journal of Animal Science

DOI:https://doi.org/10.1093/jas/skaa403· OSTI ID:2287675

Zhu, Shanli ^[1]; Portman, Mark ^[2]; Cleveland, Beth M. ^[3]; Magnuson, Andrew D. ^[4]; Wu, Kun ^[4]; Sealey, Wendy ^[2]; ^[4]

Cornell University, Ithaca, NY (United States); Jinhua Polytechnic (China); Animal Science Department, Cornell University
U.S. Fish and Wildlife Service, Bozeman, MT (United States)
US Dept. of Agriculture (USDA), Kearneysville, WV (United States)
Cornell University, Ithaca, NY (United States)

Dietary fish oil supplementation provides n-3 long-chained polyunsaturated fatty acids for supporting fish growth and metabolism and enriching fillet with eicosapentaenoic acid (EPA; 20:5n-3) and docosahexaenoic acid (DHA; c22:6n-3). Two experiments were performed as a 3 × 2 factorial arrangement of dietary treatments for 16 wk to determine effects and mechanisms of replacing 0%, 50%, and 100% fish oil with DHA-rich microalgae in combination with synthetic vs. microalgal source of astaxanthin in plant protein meal (PM)- or fishmeal (FM)- based diets for juvenile rainbow trout (Oncorhynchus mykiss). Fish (22 ± 0.26 g) were stocked at 17/tank and 3 tanks/diet. The 100% fish oil replacement impaired (P < 0.0001) growth performance, dietary protein and energy utilization, body indices, and tissue accumulation of DHA and EPA in both diet series. Here, the impairments were associated (P < 0.05) with upregulation of hepatic gene expression related to growth (ghr1and igf1) and biosynthesis of DHA and EPA (fads6 and evol5) that was more dramatic in the FM than PM diet-fed fish, and more pronounced on tissue EPA than DHA concentrations. The source of astaxanthin exerted interaction effects with the fish oil replacement on several measures including muscle total cholesterol concentrations. In conclusion, replacing fish oil by the DHA-rich microalgae produced more negative metabolic responses than the substitution of synthetic astaxanthin by the microalgal source in juvenile rainbow trout fed 2 types of practical diets.

View Accepted Manuscript (DOE)

Research Organization:: Duke University, Durham, NC (United States)

Sponsoring Organization:: USDA; USDOE

Grant/Contract Number:: EE0007091

OSTI ID:: 2287675

Alternate ID(s):: OSTI ID: 1848484
OSTI ID: 2287684

Journal Information:: Journal of Animal Science, Journal Name: Journal of Animal Science Journal Issue: 1 Vol. 99; ISSN 0021-8812

Publisher:: American Society of Animal Science - Oxford University PressCopyright Statement

Country of Publication:: United States

Language:: English

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59 BASIC BIOLOGICAL SCIENCES
Astaxanthin
fish oil
microalgae
n-3 polyunsaturated fatty acid
rainbow trout
sustainability
sustainability.

Replacing fish oil and astaxanthin by microalgal sources produced different metabolic responses in juvenile rainbow trout fed 2 types of practical diets

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