Novel of core-shell AlOOH/Cu nanostructures: Synthesis, characterization, antimicrobial activity and in vitro toxicity in Neuro-2a cells

Journal Article · Tue Aug 02 00:00:00 EDT 2016 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.4960222· OSTI ID:22608266

Bakina, O. V., E-mail: [e-mail]; Fomenko, A. N., E-mail: [e-mail]; Korovin, M. S., E-mail: [e-mail]; Glazkova, E. A., E-mail: [e-mail]; Svarovskaya, N. V., E-mail: [e-mail] ^[1]; National Research Tomsk Polytechnic University, Lenin Avenue 30, Tomsk, 634050 ^[2]

---

1. Institute of Strength Physics and Materials Sciences SB RAS, Akademicheskii Pr. 2/4, Tomsk, 634055 (Russian Federation)
2. (Russian Federation)

Core-shell micro/nanostructures were fabricated by the reaction of Al/Cu bimetallic nanoparticles with water. Al/Cu nanoparticles have been obtained using the method of simultaneous electrical explosion of a pair of the corresponding metal wires in an argon atmosphere. The nanoparticles are chemically active and interact with water at 60°C to form core-shell micro/nanostructures. The obtained products were characterized by means of X-ray diffraction, scanning electron microscopy, transmission electron microscopy and dynamic light scattering and the nitrogen adsorption method. The antibacterial activity of the synthesized structures was investigated against E. coli and St. aureus. The toxic effect of these nanostructures against the Neuro-2a neuroblastoma cell line was investigated. AlOOH/Cu nanostructures are shown to inhibit cell proliferation. The AlOOH/Cu nanostructures are good candidates for medical applications.

• OSTI ID: 22608266
• Journal Information: AIP Conference Proceedings, Vol. 1760, Issue 1; Conference: PC'16: International conference on physics of cancer: Interdisciplinary problems and clinical applications 2016, Tomsk (Russian Federation), 22-25 Mar 2016; Other Information: (c) 2016 Author(s); Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

77 NANOSCIENCE AND NANOTECHNOLOGY
ADSORPTION
ALUMINIUM COMPOUNDS
CELL PROLIFERATION
COPPER COMPOUNDS
EXPLOSIONS
IN VITRO
LIGHT SCATTERING
MICROSTRUCTURE
NANOPARTICLES
NANOSTRUCTURES
NEOPLASMS
NITROGEN
SCANNING ELECTRON MICROSCOPY
SYNTHESIS
TOXICITY
TRANSMISSION
TRANSMISSION ELECTRON MICROSCOPY
X-RAY DIFFRACTION