Non-invasive toluene sensor for early diagnosis of lung cancer

Journal Article · Wed Apr 13 00:00:00 EDT 2016 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.4945199· OSTI ID:22591090

Saxena, Rahul; Srivastava, Sudha ^[1]

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1. Department of Biotechnology, Jaypee Institute of Information Technology, A-10, Sector-62, Noida-201307,Uttar Pradesh (India)

Here we present, quantification of volatile organic compounds in human breath for early detection of lung cancer to increase survival probability. Graphene oxide nanosheets synthesized by modified Hummer’s method were employed as a sensing element to detect the presence of toluene in the sample. Optical and morphological characterization of synthesized nanomaterial was performed by UV-Visible spectroscopy and scanning electron microscopy (SEM) respectively. Spectroscopic assay shows a linearly decreasing intensity of GO absorption peak with increasing toluene concentration with a linear range from 0-200 pM. While impedimetric sensor developed on a graphene oxide nanosheetsmodified screen printed electrodes displayed a decreasing electron transfer resistance increasing toluene with much larger linear range of 0-1000 pM. Reported techniques are advantageous as these are simple, sensitive and cost effective, which can easily be extended for primary screening of other VOCs.

• OSTI ID: 22591090
• Journal Information: AIP Conference Proceedings, Vol. 1724, Issue 1; Conference: ETMN-2015: 2. international conference on emerging technologies: Micro to nano 2015, Rajasthan (India), 24-25 Oct 2015; Other Information: (c) 2016 Author(s); Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

60 APPLIED LIFE SCIENCES
ABSORPTION SPECTROSCOPY
CARBON OXIDES
CONCENTRATION RATIO
DIAGNOSIS
ELECTRIC CONDUCTIVITY
ELECTRODES
ELECTRON TRANSFER
GRAPHENE
LUNGS
NANOMATERIALS
NANOSTRUCTURES
NEOPLASMS
SCANNING ELECTRON MICROSCOPY
SCREENING
SENSORS
TOLUENE
ULTRAVIOLET SPECTRA
VISIBLE SPECTRA
VOLATILE MATTER
VOLATILITY