skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Modeling cutinase enzyme regulation in polyethylene terepthalate plastic biodegradation

Abstract

PET (Polyethylene terephthalate) is a plastic material that is commonly used in our daily life. The high production of PET and others plastics that can be up to three hundred million tons per year, is not matched by its degradation rate and hence leads to environmental pollution. To overcome this problem, we develop a biodegradation system. This system utilizes LC Cutinase enzyme produced by engineered escherichia coli bacteria to degrade PET. To make the system works efficaciously, it is important to understand the mechanism underlying its enzyme regulation. Therefore, we construct a mathematical model to describe the regulation of LC Cutinase production. The stability of the model is analyzed. We show that the designated biodegradation system can give an oscillatory behavior that is very important to control the amount of inclusion body (the miss-folded proteins that reduce the efficiency of the biodegradation system).

Authors:
 [1]; ;  [2]
  1. Department of Mathematics, Institut Teknologi Bandung, Jalan Ganeca 10 Bandung, 40132 (Indonesia)
  2. School of Life Sciences and Technology, Institut Teknologi Bandung, Jalan Ganeca 10 Bandung, 40132 (Indonesia)
Publication Date:
OSTI Identifier:
22591049
Resource Type:
Journal Article
Journal Name:
AIP Conference Proceedings
Additional Journal Information:
Journal Volume: 1723; Journal Issue: 1; Conference: SYMOMATH 2015: Symposium on biomathematics, Bandung (Indonesia), 4-6 Nov 2015; Other Information: (c) 2016 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); Journal ID: ISSN 0094-243X
Country of Publication:
United States
Language:
English
Subject:
71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; 37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; BIODEGRADATION; EFFICIENCY; ENZYMES; ESCHERICHIA COLI; MATHEMATICAL MODELS; PLASTICS; POLYESTERS; POLYETHYLENES; SIMULATION; STABILITY

Citation Formats

Apri, M., E-mail: m.apri@math.itb.ac.id, Silmi, M., Heryanto, T. E., and Moeis, M. R. Modeling cutinase enzyme regulation in polyethylene terepthalate plastic biodegradation. United States: N. p., 2016. Web. doi:10.1063/1.4945061.
Apri, M., E-mail: m.apri@math.itb.ac.id, Silmi, M., Heryanto, T. E., & Moeis, M. R. Modeling cutinase enzyme regulation in polyethylene terepthalate plastic biodegradation. United States. doi:10.1063/1.4945061.
Apri, M., E-mail: m.apri@math.itb.ac.id, Silmi, M., Heryanto, T. E., and Moeis, M. R. Wed . "Modeling cutinase enzyme regulation in polyethylene terepthalate plastic biodegradation". United States. doi:10.1063/1.4945061.
@article{osti_22591049,
title = {Modeling cutinase enzyme regulation in polyethylene terepthalate plastic biodegradation},
author = {Apri, M., E-mail: m.apri@math.itb.ac.id and Silmi, M. and Heryanto, T. E. and Moeis, M. R.},
abstractNote = {PET (Polyethylene terephthalate) is a plastic material that is commonly used in our daily life. The high production of PET and others plastics that can be up to three hundred million tons per year, is not matched by its degradation rate and hence leads to environmental pollution. To overcome this problem, we develop a biodegradation system. This system utilizes LC Cutinase enzyme produced by engineered escherichia coli bacteria to degrade PET. To make the system works efficaciously, it is important to understand the mechanism underlying its enzyme regulation. Therefore, we construct a mathematical model to describe the regulation of LC Cutinase production. The stability of the model is analyzed. We show that the designated biodegradation system can give an oscillatory behavior that is very important to control the amount of inclusion body (the miss-folded proteins that reduce the efficiency of the biodegradation system).},
doi = {10.1063/1.4945061},
journal = {AIP Conference Proceedings},
issn = {0094-243X},
number = 1,
volume = 1723,
place = {United States},
year = {2016},
month = {4}
}