Preparation of silver-chitosan nanocomposites and coating on bandage for antibacterial wound dressing application

Journal Article · Mon Feb 08 00:00:00 EST 2016 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.4941481· OSTI ID:22494611

Susilowati, Endang; Ashadi, ^[1]; Maryani, ^[2]

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1. Chemistry Education Department, Faculty of Teacher Training and Education, Universitas Sebelas Maret Surakarta (Indonesia)
2. Medical Doctor Program, Faculty of Medicine, Universitas Sebelas Maret Surakarta, Indonesia Jl. Ir Sutami 36 A Surakarta Indonesia 53126 (Indonesia)

Bandage is a medical device that is essential for wound dressing. To improve the performance of the bandage, it has been coated by silver-chitosan nanocomposites (Ag/Chit) with pad-dry-cure method. The nanocomposites were performed by chemical reduction method at room temperature using glucose as reducing agent, sodium hydroxide (NaOH) as accelerator reagent, silver nitrate (AgNO{sub 3}) as metal precursor and chitosan as stabilizing agent. Localized surface plasmon resonance (LSPR) absorption band of silver nanoparticles was investigated using UV-Vis spectrophotometer. The bandage coated Ag/Chit nanocomposites (B-Ag/Chit) were characterized by fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and scanning electron microscope (SEM). In addition, antibacterial activity of the bandage toward Gram positive (Staphylococcus aureus) and Gram negative (Escherichia coli) were also studied. The formation of silver nanoparticles was confirmed by the appearance of LSPR absorption peak at 412.2 – 423.2 nm. Coating of nanocomposite cause increasing rigidity of bandage and decreasing on crystallinity. The bandages of B-Ag/Chit demonstrated good activity against both Gram positive (S. aureus) and Gram negative (E.Coli). Thus the bandages have a potential to be used for antibacterial wound dressing application.

• OSTI ID: 22494611
• Journal Information: AIP Conference Proceedings, Vol. 1710, Issue 1; Conference: NNS2015: 6. nanoscience and nanotechnology symposium, Surakarta (Indonesia), 4-5 Nov 2015; Other Information: (c) 2016 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
ABSORPTION
AMINO ACIDS
ESCHERICHIA COLI
FOURIER TRANSFORM SPECTROMETERS
FOURIER TRANSFORMATION
GLUCOSE
INFRARED SPECTRA
NANOCOMPOSITES
NANOPARTICLES
OLIGOSACCHARIDES
REDUCING AGENTS
REDUCTION
SCANNING ELECTRON MICROSCOPY
SILVER
SILVER NITRATES
SODIUM HYDROXIDES
SPECTROPHOTOMETERS
STAPHYLOCOCCUS
TEMPERATURE RANGE 0273-0400 K
X-RAY DIFFRACTION