Development of a phase-sensitive Fourier domain optical coherence tomography system to measure mouse organ of Corti vibrations in two cochlear turns

Journal Article · Thu Dec 31 00:00:00 EST 2015 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.4939345· OSTI ID:22494508

Ramamoorthy, Sripriya ^[1]; Zhang, Yuan; Jacques, Steven ^[2]; Petrie, Tracy; Wang, Ruikang ^[3]; Nuttall, Alfred L. ^[1]

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1. Oregon Hearing Research Center, Oregon Health & Science University, Portland, Oregon (United States)
2. Department of Biomedical Engineering, Oregon Health & Science University, Portland, Oregon (United States)
3. Department of Bioengineering, University of Washington, Seattle, Washington (United States)

In this study, we have developed a phase-sensitive Fourier-domain optical coherence tomography system to simultaneously measure the in vivo inner ear vibrations in the hook area and second turn of the mouse cochlea. This technical development will enable measurement of intra-cochlear distortion products at ideal locations such as the distortion product generation site and reflection site. This information is necessary to un-mix the complex mixture of intra-cochlear waves comprising the DPOAE and thus leads to the non-invasive identification of the local region of cochlear damage.

• OSTI ID: 22494508
• Journal Information: AIP Conference Proceedings, Vol. 1703, Issue 1; Conference: 12. international workshop on the mechanics of hearing, Cape Sounio (Greece), 23-29 Jun 2014; Other Information: (c) 2015 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

60 APPLIED LIFE SCIENCES
71 CLASSICAL AND QUANTUM MECHANICS
GENERAL PHYSICS
AUDITORY ORGANS
DAMAGE
IN VIVO
MICE
OPTICAL EQUIPMENT
REFLECTION
TOMOGRAPHY