Optical coherence tomography (OCT) leading to more insight into cochlear mechanics

Journal Article · Thu Dec 31 04:00:00 EST 2015 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.4939338· OSTI ID:22494505

Boer, Egbert de ^[1]; Chen, Fangyi; Zha, Dingjun; Nuttall, Alfred L. ^[2]

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1. Academic Medical Centre, University of Amsterdam, Amsterdam (Netherlands)
2. Oregon Health & Science University, Portland, Oregon (United States)

Optical Coherence Tomography (OCT) was used to measure vibrations of the basilar membrane (BM) and the Reticular Lamina (RL) in the cochlea of the guinea pig, at frequencies up to 25 kHz. Because of the difficulty of the experiments the data have limited sets of parameters and are subject to high noise levels. In a viable guinea-pig cochlea, the RL moves in the region of maximum response with a larger amplitude than the BM. We cannot rule out that some of that difference is due to a geometrical factor. We also found a consistent increase of this amplitude difference with frequency, which points to a low-pass filtering process. That process might be linked to the mass of the fluid contained in the Organ of Corti channel (OoC channel)

• OSTI ID: 22494505
• Journal Information: AIP Conference Proceedings, Journal Name: AIP Conference Proceedings Journal Issue: 1 Vol. 1703; ISSN APCPCS; ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

71 CLASSICAL AND QUANTUM MECHANICS
GENERAL PHYSICS
AMPLITUDES
FILTERS
GUINEA PIGS
KHZ RANGE 01-100
MECHANICS
MEMBRANES
NOISE
TOMOGRAPHY