BrachyView, a novel in-body imaging system for HDR prostate brachytherapy: Experimental evaluation
- Faculty of Engineering and Information Technology, University of Technology, Sydney 2007 (Australia)
- St George Hospital Cancer Care Centre, Kogarah 2217 (Australia)
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milan 20133 (Italy)
- Memorial Sloan Kettering Cancer Center, New York, New York 10065 (United States)
Purpose: This paper presents initial experimental results from a prototype of high dose rate (HDR) BrachyView, a novel in-body source tracking system for HDR brachytherapy based on a multipinhole tungsten collimator and a high resolution pixellated silicon detector array. The probe and its associated position estimation algorithms are validated and a comprehensive evaluation of the accuracy of its position estimation capabilities is presented. Methods: The HDR brachytherapy source is moved through a sequence of positions in a prostate phantom, for various displacements in x, y, and z. For each position, multiple image acquisitions are performed, and source positions are reconstructed. Error estimates in each dimension are calculated at each source position and combined to calculate overall positioning errors. Gafchromic film is used to validate the accuracy of source placement within the phantom. Results: More than 90% of evaluated source positions were estimated with an error of less than one millimeter, with the worst-case error being 1.3 mm. Experimental results were in close agreement with previously published Monte Carlo simulation results. Conclusions: The prototype of HDR BrachyView demonstrates a satisfactory level of accuracy in its source position estimation, and additional improvements are achievable with further refinement of HDR BrachyView’s image processing algorithms.
- OSTI ID:
- 22482437
- Journal Information:
- Medical Physics, Vol. 42, Issue 12; Other Information: (c) 2015 American Association of Physicists in Medicine; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-2405
- Country of Publication:
- United States
- Language:
- English
Similar Records
BrachyView: Proof-of-principle of a novel in-body gamma camera for low dose-rate prostate brachytherapy
Prostate CT segmentation method based on nonrigid registration in ultrasound-guided CT-based HDR prostate brachytherapy