Finite element analysis of temperature controlled coagulation in laser irradiated tissue

Journal Article · Mon Jan 01 04:00:00 EST 1996 · IEEE Transactions on Bio-Medical Engineering

DOI:https://doi.org/10.1109/10.477703· OSTI ID:224491

Glenn, T N ^[1]; Rastegar, S ^[2]; Jacques, S L ^[3]

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1. Rice Univ., Houston, TX (United States)
2. Texas A&M Univ., College Station, TX (United States)
3. Univ. of Texas, Houston, TX (United States)

The Theoretical study of thermal damage processes in laser irradiated tissue provides further insight into the design of optimal coagulation procedures. Controlled laser coagulation of tissue was studied theoretically using a finite element method with a modulating laser heat source to simulate feedback controlled laser delivery with a constant surface temperature. The effects of uncertainty in scattering and absorption properties of the tissue, thermal denaturation induced changes in optical properties, and surface convection were analyzed. Compared to a single pulse CW irradiation in which a doctor would presumably stop CW laser delivery after noticing some effect such as vaporization or carbonization, the constant surface temperature scenario provided a better overall control over the coagulation process. In particular, prediction of coagulative damage in a constant temperature scenario was less sensitive to uncertainties in optical properties and their dynamic changes during the course of coagulation. Also, subsurface overheating under surface convective conditions could be compensated for under constant temperature irradiation by lowering the surface temperature. 46 refs., 9 figs., 1 tab.

• OSTI ID: 224491
• Journal Information: IEEE Transactions on Bio-Medical Engineering, Journal Name: IEEE Transactions on Bio-Medical Engineering Journal Issue: 1 Vol. 43; ISSN IEBEAX; ISSN 0018-9294
• Country of Publication: United States
• Language: English

Related Subjects

42 ENGINEERING
55 BIOLOGY AND MEDICINE
BASIC STUDIES
99 GENERAL AND MISCELLANEOUS
ANIMAL TISSUES
CONVECTION
FINITE ELEMENT METHOD
LASER RADIATION
MATHEMATICAL MODELS
PHOTOCHEMICAL REACTIONS
RADIATION EFFECTS
SURFACES
TEMPERATURE CONTROL
USES