Laser ablation of biological tissue

Thesis/Dissertation · Thu Jan 01 04:00:00 EST 1987

OSTI ID:5511918

Rastegar, S

The problem of laser ablation of biological tissue was investigated from an optical and thermodynamical point of view. The basic physical events of the process are described based on laboratory experiments and theoretical analyses. Factors such as optical properties, geometrical conditions and energy deposition rates and durations, which determine the ablation velocity and temperature field, are discussed and analyzed. Experiments were conducted using an Argon laser on samples of agar gel mixed with dye to serve as a tissue model, simulating variation of properties by variation of dye concentration. Rods of gel with diameter about the size of the laser beam diameter were used to simulate one dimensional ablation process. A theoretical analysis of the ablation process based on the heat conduction equation and an ablation interface energy balance equation was used to compute the ablation front positions and temperature fields. Arrhenius-Henriques model for thermochemical damage was combined with an analytical solution of the ablation problem was to measure the extent of irreversible damage in a tissue under laser irradiation.

• Research Organization: Texas Univ., Austin, TX (USA)
• OSTI ID: 5511918
• Country of Publication: United States
• Language: English

Related Subjects

560400* -- Other Environmental Pollutant Effects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL TISSUES
BIOLOGICAL EFFECTS
BODY
ELECTROMAGNETIC RADIATION
GAS LASERS
LASER RADIATION
LASERS
OPTICAL PROPERTIES
PATHOLOGICAL CHANGES
PHYSICAL PROPERTIES
RADIATIONS
SIMULATION
THERMODYNAMICS
TISSUES