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Using gold nanorods labelled with antibodies under the photothermal action of NIR laser radiation on Staphylococcus aureus

Journal Article · · Quantum Electronics (Woodbury, N.Y.)
; ; ;  [1]; ;  [2];  [3]
  1. N.G. Chernyshevsky Saratov State University, Saratov (Russian Federation)
  2. Institute of Applied Physics 'Nello Carrara', National Research Council, via Madonna del Piano 10 50019 Sesto Fiorentino (Italy)
  3. University of Florence, Dept. Experimental and Clinical Biomedical Sciences, viale Morgagni 50, 50134 Firenze (Italy)

The effect of NIR laser radiation (808 nm) and gold nanorods on the cells of two strains of Staphylococcus aureus, one of them being methicillin-sensitive and the other being methicillinresistant, is studied. Nanorods having the dimensions 10 × 44 nm with the absorption maximum in the NIR spectral region, functionalised with human immunoglobulins IgA and IgG, are synthesised. It is shown that the use of nanoparticles in combination with NIR irradiation leads to killing up to 97% of the population of microorganisms. (laser biophotonics)

OSTI ID:
22395844
Journal Information:
Quantum Electronics (Woodbury, N.Y.), Journal Name: Quantum Electronics (Woodbury, N.Y.) Journal Issue: 7 Vol. 44; ISSN 1063-7818
Country of Publication:
United States
Language:
English

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