Investigation of potential polyatomic interferences on uranium isotope ratio measurements for the LS-APGD-Orbitrap MS system

Goodwin, Joseph V.; Manard, Benjamin T.; Ticknor, Brian W.; Cable-Dunlap, Paula; Kenneth Marcus, R.

doi:10.1016/j.microc.2023.109645

Title: Investigation of potential polyatomic interferences on uranium isotope ratio measurements for the LS-APGD-Orbitrap MS system

Journal Article · Mon Nov 13 00:00:00 EST 2023 · Microchemical Journal

DOI:https://doi.org/10.1016/j.microc.2023.109645· OSTI ID:2224194

^[1];

^[2];

^[2]; Cable-Dunlap, Paula ^[2]; Kenneth Marcus, R. ^[1]

Clemson Univ., SC (United States)
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

The determination of actinide (e.g., U and Pu) content and isotopics is of importance to the nuclear forensics and safeguards communities. However, in the analysis of environmental samples, such as those collected by the International Atomic Energy Agency, uranium measurements can be complicated by isobaric interferences from polyatomic variants of heavy elements (e.g., Pb). This leads to complex, time-consuming sample manipulations (i.e., separations) before determining isotope ratios. An alternative strategy to sample pretreatment is to use high-resolution mass spectrometric platforms during the analysis to fully resolve the uranium isotopes from potential polyatomic interferences, negating the need for prior chemical separation. The liquid sampling - atmospheric pressure glow discharge (LS-APGD) coupled with an Orbitrap mass spectrometer provides a high-resolution (>70,000 m/Δm at m/z 200) inorganic mass spectrometry platform. Further, as a demonstration of the power of this instrumental platform, and indeed, the high-resolution approach in general, uranium isotope ratios were determined in the presence of elemental impurities (e.g., Pb, Pt, Ta, W) commonly encountered with environmental sample swipe analysis, without any prior treatment. Even at elemental impurity concentrations of 1000–5000× relative to uranium, no interference was observed with the ²³⁵U or ²³⁸U signal. In addition, the ²³⁵U/²³⁸U isotope ratio for the samples with the concomitants present are within 2 standard deviations of the values obtained without their addition, indicating that these impurities do not impact the determined uranium isotope ratio. These findings represent a significant first step in leveraging the high resolution of the LS-APGD-Orbitrap-MS to overcome isobaric and molecular interferences instead of relying on chemical separations.

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Research Organization:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Organization:: USDOE National Nuclear Security Administration (NNSA)

Grant/Contract Number:: AC05-00OR22725

OSTI ID:: 2224194

Journal Information:: Microchemical Journal, Vol. 196, Issue 1; ISSN 0026-265X

Publisher:: ElsevierCopyright Statement

Country of Publication:: United States

Language:: English

References (43)

Assessment of plutonium measurement in the femtogram range by ICP-MS; correction from interfering polyatomic species Pointurier, Fabien; Hémet, Philippe; Hubert, Amélie J. Anal. At. Spectrom., Vol. 23, Issue 1 https://doi.org/10.1039/B708568K	journal	January 2008
Automated Separation of Uranium and Plutonium from Environmental Swipe Samples for Multiple Collector Inductively Coupled Plasma Mass Spectrometry Metzger, Shalina C.; Ticknor, Brian W.; Rogers, Kayron T. Analytical Chemistry, Vol. 90, Issue 15 https://doi.org/10.1021/acs.analchem.8b02095	journal	June 2018
Coupling of the Liquid Sampling–Atmospheric Pressure Glow Discharge to Orbitrap Mass Analyzers for Uranium Isotope Ratio Analysis: Evolution of the Methodology and Implications to the Field Koppenaal, David W.; Marcus, R. Kenneth Applied Spectroscopy, Vol. 77, Issue 8 https://doi.org/10.1177/00037028221147927	journal	January 2023
Rapid and automated separation of uranium ore concentrates for trace element analysis by inductively coupled plasma – optical emission spectroscopy/triple quadrupole mass spectrometry Manard, Benjamin T.; Bostick, Debra A.; Metzger, Shalina C. Spectrochimica Acta Part B: Atomic Spectroscopy, Vol. 179 https://doi.org/10.1016/j.sab.2021.106097	journal	May 2021
Roles of collisional dissociation modalities on spectral composition and isotope ratio measurement performance of the liquid sampling – atmospheric pressure glow discharge / orbitrap mass spectrometer coupling Williams, Tyler J.; Hoegg, Edward D.; Bills, Jacob R. International Journal of Mass Spectrometry, Vol. 464 https://doi.org/10.1016/j.ijms.2021.116572	journal	June 2021
Using CO₂ Reactions to Achieve Mass-spectrometric Discrimination in Simultaneous Plutonium-isotope Speciation with Inductively Coupled Plasma–Tandem Mass Spectrometry Matsueda, Makoto; Kawakami, Tomohiko; Koarai, Kazuma Chemistry Letters, Vol. 51, Issue 7 https://doi.org/10.1246/cl.220160	journal	July 2022
Improved Uranium Isotope Ratio Analysis in Liquid Sampling–Atmospheric Pressure Glow Discharge/Orbitrap FTMS Coupling through the Use of an External Data Acquisition System Bills, Jacob R.; Nagornov, Konstantin O.; Kozhinov, Anton N. Journal of the American Society for Mass Spectrometry, Vol. 32, Issue 5 https://doi.org/10.1021/jasms.1c00051	journal	April 2021
Liquid sampling-atmospheric pressure glow discharge optical emission spectroscopy detection of laser ablation produced particles: A feasibility study Quarles, C.; Gonzalez, Jhanis; Choi, Inhee Spectrochimica Acta Part B: Atomic Spectroscopy, Vol. 76, p. 190-196 https://doi.org/10.1016/j.sab.2012.06.048	journal	October 2012
Initial Characterization and Optimization of the Liquid Sampling-Atmospheric Pressure Glow Discharge Ionization Source Coupled to an Orbitrap Mass Spectrometer for the Determination of Plutonium Goodwin, Joseph V.; Manard, Benjamin T.; Ticknor, Brian W. Analytical Chemistry, Vol. 95, Issue 32 https://doi.org/10.1021/acs.analchem.3c02367	journal	July 2023
Exploration of ICP platforms for measuring elemental impurities in uranium ore concentrates Manard, Benjamin T.; Metzger, Shalina C.; Rogers, Kayron T. International Journal of Mass Spectrometry, Vol. 455 https://doi.org/10.1016/j.ijms.2020.116378	journal	September 2020
Liquid sampling-atmospheric pressure glow discharge (LS-APGD) microplasmas for diverse spectrochemical analysis applications Marcus, R. Kenneth; Manard, Benjamin T.; Quarles, C. Derrick Journal of Analytical Atomic Spectrometry, Vol. 32, Issue 4 https://doi.org/10.1039/C7JA00008A	journal	January 2017
Mass shifts and local space charge effects observed in the quadrupole ion trap at higher resolution Cox, K. A.; Cleven, C. D.; Cooks, R. G. International Journal of Mass Spectrometry and Ion Processes, Vol. 144, Issue 1-2 https://doi.org/10.1016/0168-1176(95)04152-B	journal	May 1995
A novel method for measuring ultra-trace levels of U and Th in Au, Pt, Ir, and W matrices using ICP-QQQ-MS employing an O₂ reaction gas Harouaka, Khadouja; Hoppe, Eric W.; Arnquist, Isaac J. Journal of Analytical Atomic Spectrometry, Vol. 35, Issue 12 https://doi.org/10.1039/D0JA00220H	journal	January 2020
Initial Benchmarking of the Liquid Sampling-Atmospheric Pressure Glow Discharge-Orbitrap System Against Traditional Atomic Mass Spectrometry Techniques for Nuclear Applications Hoegg, Edward D.; Manard, Benjamin T.; Wylie, E. Miller Journal of The American Society for Mass Spectrometry, Vol. 30, Issue 2 https://doi.org/10.1007/s13361-018-2071-2	journal	October 2018
Strengthening IAEA safeguards through environmental sampling and analysis Donohue, D. L. Journal of Alloys and Compounds, Vol. 271-273 https://doi.org/10.1016/S0925-8388(98)00015-2	journal	June 1998
Ambient desorption/ionization mass spectrometry using a liquid sampling–atmospheric glow discharge (LS-APGD) ionization source Marcus, R. Kenneth; Burdette, Carolyn Q.; Manard, Benjamin T. Analytical and Bioanalytical Chemistry, Vol. 405, Issue 25 https://doi.org/10.1007/s00216-013-7216-3	journal	July 2013
Total evaporation method for uranium isotope-amount ratio measurements Mathew, K. J.; O'Connor, G.; Hasozbek, A. Journal of Analytical Atomic Spectrometry, Vol. 28, Issue 6 https://doi.org/10.1039/c2ja30321c	journal	January 2013
Evolution of Collision/Reaction Cell Technology — Advent of Triple Quadrupole ICP-MS Yamada, Noriyuki; Takahashi, Junichi BUNSEKI KAGAKU, Vol. 67, Issue 5 https://doi.org/10.2116/bunsekikagaku.67.249	journal	January 2018
Direct Uranium Isotopic Analysis of Swipe Surfaces by Microextraction-ICP-MS Manard, Benjamin T.; Rogers, Kayron T.; Ticknor, Brian W. Analytical Chemistry, Vol. 93, Issue 32 https://doi.org/10.1021/acs.analchem.1c01569	journal	July 2021
The use of carbon dioxide as the reaction cell gas for the separation of uranium and plutonium in quadrupole inductively coupled plasma mass spectrometry (ICP-MS) for nuclear forensic samples Childs, Daniel A.; Hill, Jamie G. Journal of Radioanalytical and Nuclear Chemistry, Vol. 318, Issue 1 https://doi.org/10.1007/s10967-018-5973-3	journal	August 2018
Liquid Sampling-Atmospheric Pressure Glow Discharge Ionization Source for Elemental Mass Spectrometry Marcus, R. Kenneth; Quarles, C. Derrick; Barinaga, Charles J. Analytical Chemistry, Vol. 83, Issue 7 https://doi.org/10.1021/ac200098h	journal	April 2011
Coupling of Laser Ablation and the Liquid Sampling-Atmospheric Pressure Glow Discharge Plasma for Simultaneous, Comprehensive Mapping: Elemental, Molecular, and Spatial Analysis Paing, Htoo W.; Bryant, Tyler J.; Quarles, C. Derrick Analytical Chemistry, Vol. 92, Issue 18 https://doi.org/10.1021/acs.analchem.0c02677	journal	August 2020
Observation of ion coalescence in Orbitrap Fourier transform mass spectrometry: Ion coalescence in Orbitrap FTMS Gorshkov, Mikhail V.; Fornelli, Luca; Tsybin, Yury O. Rapid Communications in Mass Spectrometry, Vol. 26, Issue 15 https://doi.org/10.1002/rcm.6289	journal	June 2012
A new method for determining 236U/238U isotope ratios in environmental samples by means OF ICP-MS/MS Diez-Fernández, Silvia; Jaegler, Hugo; Bresson, Carole Talanta, Vol. 206 https://doi.org/10.1016/j.talanta.2019.120221	journal	January 2020
Preparation and certification of the uranium nitrate solution reference materials series IRMM-2019 to IRMM-2029 for the isotopic composition Richter, S.; Venchiarutti, C.; Hennessy, C. Journal of Radioanalytical and Nuclear Chemistry, Vol. 318, Issue 2 https://doi.org/10.1007/s10967-018-6166-9	journal	September 2018
Pushing Limits of ICP–MS/MS for the Determination of Ultralow ²³⁶U/²³⁸U Isotope Ratios Jaegler, Hugo; Gourgiotis, Alkiviadis; Steier, Peter Analytical Chemistry, Vol. 92, Issue 11 https://doi.org/10.1021/acs.analchem.0c01121	journal	May 2020
Mass spectrometric analysis for nuclear safeguards Boulyga, Sergei; Konegger-Kappel, Stefanie; Richter, Stephan Journal of Analytical Atomic Spectrometry, Vol. 30, Issue 7 https://doi.org/10.1039/C4JA00491D	journal	January 2015
Development, validation and verification of an ICP-MS procedure for a multi-element analysis of uranium ore concentrates Boulyga, Sergei F.; Cunningham, J. Alan; Macsik, Zsuzsanna Journal of Analytical Atomic Spectrometry, Vol. 32, Issue 11 https://doi.org/10.1039/C7JA00180K	journal	January 2017
Conceptual Demonstration of Ambient Desorption-Optical Emission Spectroscopy Using a Liquid Sampling-Atmospheric Pressure Glow Discharge Microplasma Source Marcus, R. Kenneth; Paing, Htoo W.; Zhang, Lynn X. Analytical Chemistry, Vol. 88, Issue 11 https://doi.org/10.1021/acs.analchem.6b00751	journal	May 2016
Analysis of solid uranium particulates on cotton swipes with an automated microextraction-ICP-MS system Bradley, Veronica C.; Spano, Tyler L.; Thompson, Cyril V. Analytical Methods, Vol. 14, Issue 44 https://doi.org/10.1039/D2AY01394K	journal	January 2022
Direct isotopic analysis of solid uranium particulates on cotton swipes by microextraction-ICP-MS Bradley, Veronica C.; Spano, Tyler L.; Metzger, Shalina C. Analytica Chimica Acta, Vol. 1209 https://doi.org/10.1016/j.aca.2022.339836	journal	May 2022
Optimization of uranium and plutonium separations using TEVA and UTEVA cartridges for MC-ICP-MS analysis of environmental swipe samples Metzger, Shalina C.; Rogers, Kayron T.; Bostick, Debra A. Talanta, Vol. 198 https://doi.org/10.1016/j.talanta.2019.02.034	journal	June 2019
Sector field mass spectrometers in ICP-MS Jakubowski, Norbert; Moens, Luc; Vanhaecke, Frank Spectrochimica Acta Part B: Atomic Spectroscopy, Vol. 53, Issue 13 https://doi.org/10.1016/S0584-8547(98)00222-5	journal	November 1998
Improved uranium isotopic ratio determinations for the liquid sampling-atmospheric pressure glow discharge orbitrap mass spectrometer by use of moving average processing Goodwin, Joseph V.; Manard, Benjamin T.; Ticknor, Brian W. Journal of Analytical Atomic Spectrometry, Vol. 37, Issue 4 https://doi.org/10.1039/D1JA00374G	journal	January 2022
Peer Reviewed: Strengthened Nuclear Safeguards Donohue, David L. Analytical Chemistry, Vol. 74, Issue 1 https://doi.org/10.1021/ac021909y	journal	January 2002
Concomitant ion effects on isotope ratio measurements with liquid sampling – atmospheric pressure glow discharge ion source Orbitrap mass spectrometry Hoegg, Edward D.; Marcus, R. Kenneth; Hager, George J. Journal of Analytical Atomic Spectrometry, Vol. 33, Issue 2 https://doi.org/10.1039/C7JA00308K	journal	January 2018
Radionuclide analysis using collision–reaction cell ICP-MS technology: a review Diez-Fernández, Silvia; Isnard, Hélène; Nonell, Anthony Journal of Analytical Atomic Spectrometry, Vol. 35, Issue 12 https://doi.org/10.1039/D0JA00211A	journal	January 2020
Resolving Severe Elemental Isobaric Interferences with a Combined Atomic and Molecular Ionization Source–Orbitrap Mass Spectrometry Approach: The ⁸⁷Sr and ⁸⁷Rb Geochronology Pair Hoegg, Edward D.; Godin, Simon; Szpunar, Joanna Analytical Chemistry, Vol. 93, Issue 33 https://doi.org/10.1021/acs.analchem.1c01795	journal	August 2021
Direct analysis of cotton swipes for plutonium isotope determination by microextraction-ICP-MS Manard, Benjamin T.; Metzger, Shalina C.; Rogers, Kayron T. Journal of Analytical Atomic Spectrometry, Vol. 36, Issue 10 https://doi.org/10.1039/D1JA00255D	journal	January 2021
Rapid Determination of Uranium Isotopic Abundance from Cotton Swipes: Direct Extraction via a Planar Surface Reader and Coupling to a Microplasma Ionization Source Paing, Htoo W.; Manard, Benjamin T.; Ticknor, Brian W. Analytical Chemistry, Vol. 92, Issue 12 https://doi.org/10.1021/acs.analchem.0c01606	journal	June 2020
A multi-electrode glow discharge ionization source for atomic and molecular mass spectrometry Hoegg, Edward D.; Williams, Tyler J.; Bills, Jacob R. Journal of Analytical Atomic Spectrometry, Vol. 35, Issue 9 https://doi.org/10.1039/D0JA00142B	journal	January 2020
Strategies to develop methods using ion-molecule reactions in a quadrupole reaction cell to overcome spectral overlaps in inductively coupled plasma mass spectrometry Olesik, John W.; Jones, Deanna R. J. Anal. At. Spectrom., Vol. 21, Issue 2 https://doi.org/10.1039/B511464K	journal	January 2006
Polyatomic interferences on high precision uranium isotope ratio measurements by MC-ICP-MS: applications to environmental sampling for nuclear safeguards Pollington, Anthony D.; Kinman, William S.; Hanson, Susan K. Journal of Radioanalytical and Nuclear Chemistry, Vol. 307, Issue 3 https://doi.org/10.1007/s10967-015-4419-4	journal	September 2015

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Title: Investigation of potential polyatomic interferences on uranium isotope ratio measurements for the LS-APGD-Orbitrap MS system

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