Examination of adipose depot-specific PPAR moieties

Journal Article · Fri Apr 02 00:00:00 EDT 2010 · Biochemical and Biophysical Research Communications

DOI:https://doi.org/10.1016/J.BBRC.2010.02.170· OSTI ID:22202438

Vierck, J. L. ^[1]; Hausman, G. J. ^[2]; Guan, L. L. ^[3]; Fernyhough, M. E. ^[4]; Poulos, S. P. ^[5]; Mir, P. S. ^[6]; Jiang, Z. ^[1]

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1. Department of Animal Sciences, Washington State University, Pullman, WA 99164 (United States)
2. USDA-ARS, Richard B. Russell Agricultural Research Station, Athens, GA 30604 (United States)
3. Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, T6G 2P5 Canada (Canada)
4. The Hartz Mountain Corporation, Secaucus, NJ 07094 (United States)
5. The Coca-Cola Company, Research and Technology, Atlanta, GA 30313 (United States)
6. Agriculture and Agri-Food Canada Research Centre, Lethbridge, CA T1J 4B1 (United States)

Molecular mechanisms of peroxisome proliferator activated receptors (PPARs) are being defined rapidly, as illustrated by the volume of papers published. Much of the research is directed towards a clinical end-point/application; however, the non-homogeneous nature of adipose depots in laboratory animals is spurring similar research in domestic meat animals (such as beef cattle). Moreover, the size of adipose depots in meat animals remains an attractive feature for using them to obtain cells for PPAR research. Examination of meat-animal depot-specific PPAR moieties may provide novel information about adipocyte regulation that might be extrapolated to all animals.

• OSTI ID: 22202438
• Journal Information: Biochemical and Biophysical Research Communications, Journal Name: Biochemical and Biophysical Research Communications Journal Issue: 2 Vol. 394; ISSN 0006-291X; ISSN BBRCA9
• Country of Publication: United States
• Language: English

Related Subjects

60 APPLIED LIFE SCIENCES
CATTLE
GENE REGULATION
LABORATORY ANIMALS
MEAT
RECEPTORS